Extra-Virgin Olive Oil Enhances the Blood–Brain Barrier Function in Mild Cognitive Impairment: A Randomized Controlled Trial

Extra-Virgin Olive Oil Enhances the Blood–Brain Barrier Function in Mild Cognitive Impairment: A Randomized Controlled Trial

Mild cognitive impairment (MCI) and early Alzheimer’s disease (AD) are characterized by blood–brain barrier (BBB) breakdown leading to abnormal BBB permeability ahead of brain atrophy or dementia. Previous findings in AD mouse models have reported the beneficial effect of extra-virgin olive oil (EVO...

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Bibliographic Details
Main Authors: Amal Kaddoumi, Thomas S. Denney, Gopikrishna Deshpande, Jennifer L. Robinson, Ronald J. Beyers, David T. Redden, Domenico Praticò, Tassos C. Kyriakides, Bonian Lu, Anna N. Kirby, Darren T. Beck, Nancy D. Merner
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Nutrients
Subjects:
Alzheimer’s disease
mild cognitive impairment
blood–brain barrier
contrast-enhanced MRI
functional MRI
extra-virgin olive oil
Online Access:https://www.mdpi.com/2072-6643/14/23/5102

Internet

https://www.mdpi.com/2072-6643/14/23/5102

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