Insecticide mixtures for mosquito net impregnation against malaria vectors
Insecticides belonging to the pyrethroid family are the only compounds currently available for the treatment of mosquito nets. Unfortunately, some malaria vector species have developed resistance to pyrethroids and the lack of alternative chemical categories is a great concern. One strategy for resi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2002-09-01
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| Series: | Parasite |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1051/parasite/2002093255 |
| _version_ | 1797427203745513472 |
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| author | Corbel V. Darriet F. Chandre F. Hougard J.M. |
| author_facet | Corbel V. Darriet F. Chandre F. Hougard J.M. |
| author_sort | Corbel V. |
| collection | DOAJ |
| description | Insecticides belonging to the pyrethroid family are the only compounds currently available for the treatment of mosquito nets. Unfortunately, some malaria vector species have developed resistance to pyrethroids and the lack of alternative chemical categories is a great concern. One strategy for resistance management would be to treat mosquito nets with a mixture associating two insecticides having different modes of action. This study presents the results obtained with insecticide mixtures containing several proportions of bifenthrin (a pyrethroid insecticide) and carbosulfan (a carbamate insecticide). The mixtures were sprayed on mosquito net samples and their efficacy were tested against a susceptible strain of Anopheles gambiae, the major malaria vector in Africa. A significant synergism was observed with a mixture containing 25 mg/m2 of bifenthrin (half the recommended dosage for treated nets) and 6.25 mg/m2 of carbosulfan (about 2 % of the recommended dosage). The observed mortality was significantly more than expected in the absence of any interaction (80 % vs 41 %) and the knock-down effect was maintained, providing an effective barrier against susceptible mosquitoes. |
| first_indexed | 2024-03-09T08:40:53Z |
| format | Article |
| id | doaj.art-657aa7bcc2474e628eb81cc820fa9460 |
| institution | Directory Open Access Journal |
| issn | 1252-607X 1776-1042 |
| language | English |
| last_indexed | 2024-03-09T08:40:53Z |
| publishDate | 2002-09-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Parasite |
| spelling | doaj.art-657aa7bcc2474e628eb81cc820fa94602023-12-02T16:47:36ZengEDP SciencesParasite1252-607X1776-10422002-09-019325525910.1051/parasite/2002093255parasite2002093p255Insecticide mixtures for mosquito net impregnation against malaria vectorsCorbel V.Darriet F.Chandre F.Hougard J.M.Insecticides belonging to the pyrethroid family are the only compounds currently available for the treatment of mosquito nets. Unfortunately, some malaria vector species have developed resistance to pyrethroids and the lack of alternative chemical categories is a great concern. One strategy for resistance management would be to treat mosquito nets with a mixture associating two insecticides having different modes of action. This study presents the results obtained with insecticide mixtures containing several proportions of bifenthrin (a pyrethroid insecticide) and carbosulfan (a carbamate insecticide). The mixtures were sprayed on mosquito net samples and their efficacy were tested against a susceptible strain of Anopheles gambiae, the major malaria vector in Africa. A significant synergism was observed with a mixture containing 25 mg/m2 of bifenthrin (half the recommended dosage for treated nets) and 6.25 mg/m2 of carbosulfan (about 2 % of the recommended dosage). The observed mortality was significantly more than expected in the absence of any interaction (80 % vs 41 %) and the knock-down effect was maintained, providing an effective barrier against susceptible mosquitoes.http://dx.doi.org/10.1051/parasite/2002093255insecticide mixturesynergytreated mosquito netAnopheles gambiae |
| spellingShingle | Corbel V. Darriet F. Chandre F. Hougard J.M. Insecticide mixtures for mosquito net impregnation against malaria vectors Parasite insecticide mixture synergy treated mosquito net Anopheles gambiae |
| title | Insecticide mixtures for mosquito net impregnation against malaria vectors |
| title_full | Insecticide mixtures for mosquito net impregnation against malaria vectors |
| title_fullStr | Insecticide mixtures for mosquito net impregnation against malaria vectors |
| title_full_unstemmed | Insecticide mixtures for mosquito net impregnation against malaria vectors |
| title_short | Insecticide mixtures for mosquito net impregnation against malaria vectors |
| title_sort | insecticide mixtures for mosquito net impregnation against malaria vectors |
| topic | insecticide mixture synergy treated mosquito net Anopheles gambiae |
| url | http://dx.doi.org/10.1051/parasite/2002093255 |
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