Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

Abstract Background α-Synuclein (α-syn) is a pre-synaptic protein which progressively accumulates in neuronal and non-neuronal cells in neurodegenerative diseases such as Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy. Recent evidence suggests that aberrant im...

Full description

Bibliographic Details
Main Authors: Michiyo Iba, Changyoun Kim, Michelle Sallin, Somin Kwon, Anjali Verma, Cassia Overk, Robert A. Rissman, Ranjan Sen, Jyoti Misra Sen, Eliezer Masliah
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Neuroinflammation
Subjects:
α-Synuclein
T cell
Parkinson’s disease
Dementia with Lewy Bodies
Adaptive immunity
Innate immunity
Online Access:http://link.springer.com/article/10.1186/s12974-020-01888-0

Internet

http://link.springer.com/article/10.1186/s12974-020-01888-0

Similar Items