Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre Analysis
<i>Purpose:</i> Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are common in elderly men. Data on the laser-based surgery known as thulium vapoenucleation of the prostate (ThuVEP) in PCa patients are rare. Our objective was to analyse the feasibility, safety and functional...
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| Format: | Article |
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MDPI AG
2023-02-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/3/1174 |
| _version_ | 1797624053731688448 |
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| author | Tobias Lamersdorf Christopher Netsch Benedikt Becker Christian Wülfing Petra Anheuser Oliver Engel Andreas J. Gross Clemens Mathias Rosenbaum |
| author_facet | Tobias Lamersdorf Christopher Netsch Benedikt Becker Christian Wülfing Petra Anheuser Oliver Engel Andreas J. Gross Clemens Mathias Rosenbaum |
| author_sort | Tobias Lamersdorf |
| collection | DOAJ |
| description | <i>Purpose:</i> Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are common in elderly men. Data on the laser-based surgery known as thulium vapoenucleation of the prostate (ThuVEP) in PCa patients are rare. Our objective was to analyse the feasibility, safety and functional outcome of ThuVEP in patients with lower urinary tract symptoms (LUTS) and PCa. <i>Methods:</i> Multicentre study, including 1256 men who underwent ThuVEP for LUTS. Maximum urinary flow rate (Qmax) and post-void residual volume (PVR) were measured perioperatively. The International Prostate Symptome Score (IPSS) was measured perioperatively and at follow-up (FU). Perioperative complications were captured. Reoperation rate was captured at FU. <i>Results:</i> Of 994 men with complete data, 286 (28.8%) patients had PCa. The most common Gleason score was 3 + 3 in 142 patients (49.7%). Most common was low-risk PCa (141 pts; 49.3%). PCa patients were older, had smaller prostates and had higher prostate-specific antigen (PSA) values (all <i>p</i> < 0.001). Comparing non-PCa and PCa patients, no differences occurred perioperatively. IPSS, quality of life and PVR decreased (all <i>p</i> < 0.001) and Qmax improved (<i>p</i> < 0.001) in both groups. Reoperation rates did not differ. The results of low- vs. intermediate-/high-risk PCa patients were comparable. <i>Conclusion:</i> ThuVEP is a safe and long-lasting treatment option for patients with LUTS with or without PCa. No differences occurred when comparing low- to intermediate-/high-risk PCa patients. |
| first_indexed | 2024-03-11T09:37:56Z |
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| id | doaj.art-657f73a429104793b933e40b586d49df |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T09:37:56Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-657f73a429104793b933e40b586d49df2023-11-16T17:12:48ZengMDPI AGJournal of Clinical Medicine2077-03832023-02-01123117410.3390/jcm12031174Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre AnalysisTobias Lamersdorf0Christopher Netsch1Benedikt Becker2Christian Wülfing3Petra Anheuser4Oliver Engel5Andreas J. Gross6Clemens Mathias Rosenbaum7Department of Urology, Asklepios Hospital Barmbek, 22307 Hamburg, GermanyDepartment of Urology, Asklepios Hospital Barmbek, 22307 Hamburg, GermanyDepartment of Urology, Asklepios Hospital Barmbek, 22307 Hamburg, GermanyDepartment of Urology, Asklepios Hospital Altona, 22763 Hamburg, GermanyDepartment of Urology, Asklepios Hospital Wandsbek, 22043 Hamburg, GermanyDepartment of Urology, Asklepios Hospital Harburg, 21075 Hamburg, GermanyDepartment of Urology, Asklepios Hospital Barmbek, 22307 Hamburg, GermanyDepartment of Urology, Asklepios Hospital Barmbek, 22307 Hamburg, Germany<i>Purpose:</i> Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are common in elderly men. Data on the laser-based surgery known as thulium vapoenucleation of the prostate (ThuVEP) in PCa patients are rare. Our objective was to analyse the feasibility, safety and functional outcome of ThuVEP in patients with lower urinary tract symptoms (LUTS) and PCa. <i>Methods:</i> Multicentre study, including 1256 men who underwent ThuVEP for LUTS. Maximum urinary flow rate (Qmax) and post-void residual volume (PVR) were measured perioperatively. The International Prostate Symptome Score (IPSS) was measured perioperatively and at follow-up (FU). Perioperative complications were captured. Reoperation rate was captured at FU. <i>Results:</i> Of 994 men with complete data, 286 (28.8%) patients had PCa. The most common Gleason score was 3 + 3 in 142 patients (49.7%). Most common was low-risk PCa (141 pts; 49.3%). PCa patients were older, had smaller prostates and had higher prostate-specific antigen (PSA) values (all <i>p</i> < 0.001). Comparing non-PCa and PCa patients, no differences occurred perioperatively. IPSS, quality of life and PVR decreased (all <i>p</i> < 0.001) and Qmax improved (<i>p</i> < 0.001) in both groups. Reoperation rates did not differ. The results of low- vs. intermediate-/high-risk PCa patients were comparable. <i>Conclusion:</i> ThuVEP is a safe and long-lasting treatment option for patients with LUTS with or without PCa. No differences occurred when comparing low- to intermediate-/high-risk PCa patients.https://www.mdpi.com/2077-0383/12/3/1174benign prostate hyperplasiaenucleationendourologylaserprostate neoplasm |
| spellingShingle | Tobias Lamersdorf Christopher Netsch Benedikt Becker Christian Wülfing Petra Anheuser Oliver Engel Andreas J. Gross Clemens Mathias Rosenbaum Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre Analysis Journal of Clinical Medicine benign prostate hyperplasia enucleation endourology laser prostate neoplasm |
| title | Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre Analysis |
| title_full | Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre Analysis |
| title_fullStr | Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre Analysis |
| title_full_unstemmed | Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre Analysis |
| title_short | Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre Analysis |
| title_sort | influence of prostate cancer on thulium vapoenucleation of the prostate a multicentre analysis |
| topic | benign prostate hyperplasia enucleation endourology laser prostate neoplasm |
| url | https://www.mdpi.com/2077-0383/12/3/1174 |
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