Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis

Digital holographic interferometry (DHI) radiation dosimetry has been proposed as an experimental metrology technique for measuring absorbed radiation doses to water with high spatial resolution via noninvasive optical calorimetry. The process involves digitally recording consecutive interference pa...

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Main Authors: Lancia Hubley, Jackson Roberts, Juergen Meyer, Alicia Moggré, Steven Marsh
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/19/5/1167
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author Lancia Hubley
Jackson Roberts
Juergen Meyer
Alicia Moggré
Steven Marsh
author_facet Lancia Hubley
Jackson Roberts
Juergen Meyer
Alicia Moggré
Steven Marsh
author_sort Lancia Hubley
collection DOAJ
description Digital holographic interferometry (DHI) radiation dosimetry has been proposed as an experimental metrology technique for measuring absorbed radiation doses to water with high spatial resolution via noninvasive optical calorimetry. The process involves digitally recording consecutive interference patterns resulting from variations in the refractive index as a function of the radiation-absorbed dose. Experiments conducted on prototype optical systems revealed the approach to be feasible but strongly dependent on environmental-influence quantities and setup configuration. A virtual dosimeter reflecting the prototype was created in a commercial optical modelling package. A number of virtual phantoms were developed to characterize the performance of the dosimeter under ideal conditions and with simulated disruptions in environmental-influence quantities, such as atmospheric and temperature perturbations as well as mechanical vibrations. Investigations into the error response revealed that slow drifts in atmospheric parameters and heat expansion caused the measured dose to vary between measurements, while atmospheric fluctuations and vibration contributed to system noise, significantly lowering the spatial resolution of the detector system. The impact of these effects was found to be largely mitigated with equalisation of the dosimeter’s reference and object path lengths, and by miniaturising the detector. Equalising path lengths resulted in a reduction of 97.5% and 96.9% in dosimetric error introduced by heat expansion and atmospheric drift, respectively, while miniaturisation of the dosimeter was found to reduce its sensitivity to vibrations and atmospheric turbulence by up to 41.7% and 54.5%, respectively. This work represents a novel approach to optical-detector refinement in which metrics from medical imaging were adapted into software and applied to a a virtual-detector system. This methodology was found to be well-suited for the optimization of a digital holographic interferometer.
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spelling doaj.art-657fad78fbc44cdc909e3a245376cf912022-12-22T04:23:45ZengMDPI AGSensors1424-82202019-03-01195116710.3390/s19051167s19051167Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity AnalysisLancia Hubley0Jackson Roberts1Juergen Meyer2Alicia Moggré3Steven Marsh4School of Physical and Chemical Sciences, West Building, Engineering Drive, University of Canterbury Christchurch 8041, New ZealandSchool of Physical and Chemical Sciences, West Building, Engineering Drive, University of Canterbury Christchurch 8041, New ZealandRadiation Oncology Department, University of Washington Medical Center (UWMC), 1959 N.E. Pacific Street, Seattle, WA 98195, USAMedical Physics and Bioengineering, Christchurch Hospital, 2 Riccarton Avenue, Christchurch 8011, New ZealandSchool of Physical and Chemical Sciences, West Building, Engineering Drive, University of Canterbury Christchurch 8041, New ZealandDigital holographic interferometry (DHI) radiation dosimetry has been proposed as an experimental metrology technique for measuring absorbed radiation doses to water with high spatial resolution via noninvasive optical calorimetry. The process involves digitally recording consecutive interference patterns resulting from variations in the refractive index as a function of the radiation-absorbed dose. Experiments conducted on prototype optical systems revealed the approach to be feasible but strongly dependent on environmental-influence quantities and setup configuration. A virtual dosimeter reflecting the prototype was created in a commercial optical modelling package. A number of virtual phantoms were developed to characterize the performance of the dosimeter under ideal conditions and with simulated disruptions in environmental-influence quantities, such as atmospheric and temperature perturbations as well as mechanical vibrations. Investigations into the error response revealed that slow drifts in atmospheric parameters and heat expansion caused the measured dose to vary between measurements, while atmospheric fluctuations and vibration contributed to system noise, significantly lowering the spatial resolution of the detector system. The impact of these effects was found to be largely mitigated with equalisation of the dosimeter’s reference and object path lengths, and by miniaturising the detector. Equalising path lengths resulted in a reduction of 97.5% and 96.9% in dosimetric error introduced by heat expansion and atmospheric drift, respectively, while miniaturisation of the dosimeter was found to reduce its sensitivity to vibrations and atmospheric turbulence by up to 41.7% and 54.5%, respectively. This work represents a novel approach to optical-detector refinement in which metrics from medical imaging were adapted into software and applied to a a virtual-detector system. This methodology was found to be well-suited for the optimization of a digital holographic interferometer.http://www.mdpi.com/1424-8220/19/5/1167digital holographic interferometryoptical calorimetryradiation dosimetryFREDoptical modelling
spellingShingle Lancia Hubley
Jackson Roberts
Juergen Meyer
Alicia Moggré
Steven Marsh
Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
Sensors
digital holographic interferometry
optical calorimetry
radiation dosimetry
FRED
optical modelling
title Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_full Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_fullStr Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_full_unstemmed Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_short Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_sort optical radiation calorimeter refinement by virtual sensitivity analysis
topic digital holographic interferometry
optical calorimetry
radiation dosimetry
FRED
optical modelling
url http://www.mdpi.com/1424-8220/19/5/1167
work_keys_str_mv AT lanciahubley opticalradiationcalorimeterrefinementbyvirtualsensitivityanalysis
AT jacksonroberts opticalradiationcalorimeterrefinementbyvirtualsensitivityanalysis
AT juergenmeyer opticalradiationcalorimeterrefinementbyvirtualsensitivityanalysis
AT aliciamoggre opticalradiationcalorimeterrefinementbyvirtualsensitivityanalysis
AT stevenmarsh opticalradiationcalorimeterrefinementbyvirtualsensitivityanalysis