Clozapine-induced massive hematemesis: A rare case report

Clozapine (CLZ) is a drug of choice for the treatment of resistant schizophrenia. It is always blamed probably due to its life-threatening side effects, such as agranulocytosis, constipation, cardiomyopathies, and rarely hematemesis. We report the case of a 65-year-old patient diagnosed with resista...

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Main Authors: Javed Ather Siddiqui, Shazia Farheen Qureshi, Yousef Bin Ahmed Shawosh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Annals of Indian Psychiatry
Subjects:
Online Access:http://www.anip.co.in/article.asp?issn=2588-8358;year=2019;volume=3;issue=2;spage=171;epage=172;aulast=Siddiqui
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author Javed Ather Siddiqui
Shazia Farheen Qureshi
Yousef Bin Ahmed Shawosh
author_facet Javed Ather Siddiqui
Shazia Farheen Qureshi
Yousef Bin Ahmed Shawosh
author_sort Javed Ather Siddiqui
collection DOAJ
description Clozapine (CLZ) is a drug of choice for the treatment of resistant schizophrenia. It is always blamed probably due to its life-threatening side effects, such as agranulocytosis, constipation, cardiomyopathies, and rarely hematemesis. We report the case of a 65-year-old patient diagnosed with resistant schizophrenia and treated with CLZ later he developed sudden massive hematemesis. The aim of our case report is to describe the rarely seen and potentially life-threatening side effect related to CLZ. Physician, particularly psychiatrists and medical specialists, should not ignore, be aware, and alert or always need to be watchful to the fatality of CLZ-induced hematemesis in the management of psychiatric disorders and should take appropriate therapeutic measures in such a case.
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spelling doaj.art-65802da93f214b879a0302096be95a182022-12-21T23:16:11ZengWolters Kluwer Medknow PublicationsAnnals of Indian Psychiatry2588-83582588-83662019-01-013217117210.4103/aip.aip_8_19Clozapine-induced massive hematemesis: A rare case reportJaved Ather SiddiquiShazia Farheen QureshiYousef Bin Ahmed ShawoshClozapine (CLZ) is a drug of choice for the treatment of resistant schizophrenia. It is always blamed probably due to its life-threatening side effects, such as agranulocytosis, constipation, cardiomyopathies, and rarely hematemesis. We report the case of a 65-year-old patient diagnosed with resistant schizophrenia and treated with CLZ later he developed sudden massive hematemesis. The aim of our case report is to describe the rarely seen and potentially life-threatening side effect related to CLZ. Physician, particularly psychiatrists and medical specialists, should not ignore, be aware, and alert or always need to be watchful to the fatality of CLZ-induced hematemesis in the management of psychiatric disorders and should take appropriate therapeutic measures in such a case.http://www.anip.co.in/article.asp?issn=2588-8358;year=2019;volume=3;issue=2;spage=171;epage=172;aulast=Siddiquiclozapinemassive hematemesisresistant-schizophrenia
spellingShingle Javed Ather Siddiqui
Shazia Farheen Qureshi
Yousef Bin Ahmed Shawosh
Clozapine-induced massive hematemesis: A rare case report
Annals of Indian Psychiatry
clozapine
massive hematemesis
resistant-schizophrenia
title Clozapine-induced massive hematemesis: A rare case report
title_full Clozapine-induced massive hematemesis: A rare case report
title_fullStr Clozapine-induced massive hematemesis: A rare case report
title_full_unstemmed Clozapine-induced massive hematemesis: A rare case report
title_short Clozapine-induced massive hematemesis: A rare case report
title_sort clozapine induced massive hematemesis a rare case report
topic clozapine
massive hematemesis
resistant-schizophrenia
url http://www.anip.co.in/article.asp?issn=2588-8358;year=2019;volume=3;issue=2;spage=171;epage=172;aulast=Siddiqui
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AT yousefbinahmedshawosh clozapineinducedmassivehematemesisararecasereport