Comparison of New Topical Treatment (Curcumine viscous solution 30% ) For Recurrent Herpes Labialis (RHL)

Aims: To determine the therapeutic effect of viscaus solution of curcumine 30% , as a topical treatment of RHL in comparison with the traditional antiviral agent " acyclovir ". Materials and methods: A total of 120 patients (100 female, 20 male) with RHL divided into four groups: Group I:...

Full description

Bibliographic Details
Main Author: Maha T Al–Saffar
Format: Article
Language:Arabic
Published: University of Mosul, College of Dentistry 2009-08-01
Series:Al-Rafidain Dental Journal
Subjects:
Online Access:https://rden.mosuljournals.com/pdf_9108_078c0f9f63f6b81fa5a03a4ec3f14f43.html
_version_ 1819123355250327552
author Maha T Al–Saffar
author_facet Maha T Al–Saffar
author_sort Maha T Al–Saffar
collection DOAJ
description Aims: To determine the therapeutic effect of viscaus solution of curcumine 30% , as a topical treatment of RHL in comparison with the traditional antiviral agent " acyclovir ". Materials and methods: A total of 120 patients (100 female, 20 male) with RHL divided into four groups: Group I: Fifty patients used viscous solution of curcumine 30% topically. Group II: Thirty patients used viramed "acyclovir" cream topically. Group III: Twenty five patients used glycerol topically "control positive group".Group IV: Fifteen patients without treatment "control negative group". Results: Female were more affected than male with RHL (83.3% female, 16.3% male) with high percentage of association between highly stressed events and RHL. The results also showed significant differences between size of lesion, duration of healing and pain in patients using viscous curcumine solution topically and patients received viramed cream and patient received no treatment. The patients group which received glycerol "control positive" showed a significant differences in duration of healing compared with group I and group II. While, patients group which received viramed topically showed no significant differences compared with group III and IV in related to duration of pain and show significant difference with group I, III and IV in relation to duration of healing. Conclusions: Topical application of viscaus carcumine solution 30% showed a good effective response on RHL compared with other antiviral agent with the lower percentage of adverse effect, and further study for its effect on other oral lesion may be recommended.
first_indexed 2024-12-22T07:07:02Z
format Article
id doaj.art-6582249fa959495cb647863bb94e99bf
institution Directory Open Access Journal
issn 1812-1217
1998-0345
language Arabic
last_indexed 2024-12-22T07:07:02Z
publishDate 2009-08-01
publisher University of Mosul, College of Dentistry
record_format Article
series Al-Rafidain Dental Journal
spelling doaj.art-6582249fa959495cb647863bb94e99bf2022-12-21T18:34:38ZaraUniversity of Mosul, College of DentistryAl-Rafidain Dental Journal1812-12171998-03452009-08-019222523110.33899/rden.2009.9108Comparison of New Topical Treatment (Curcumine viscous solution 30% ) For Recurrent Herpes Labialis (RHL)Maha T Al–SaffarAims: To determine the therapeutic effect of viscaus solution of curcumine 30% , as a topical treatment of RHL in comparison with the traditional antiviral agent " acyclovir ". Materials and methods: A total of 120 patients (100 female, 20 male) with RHL divided into four groups: Group I: Fifty patients used viscous solution of curcumine 30% topically. Group II: Thirty patients used viramed "acyclovir" cream topically. Group III: Twenty five patients used glycerol topically "control positive group".Group IV: Fifteen patients without treatment "control negative group". Results: Female were more affected than male with RHL (83.3% female, 16.3% male) with high percentage of association between highly stressed events and RHL. The results also showed significant differences between size of lesion, duration of healing and pain in patients using viscous curcumine solution topically and patients received viramed cream and patient received no treatment. The patients group which received glycerol "control positive" showed a significant differences in duration of healing compared with group I and group II. While, patients group which received viramed topically showed no significant differences compared with group III and IV in related to duration of pain and show significant difference with group I, III and IV in relation to duration of healing. Conclusions: Topical application of viscaus carcumine solution 30% showed a good effective response on RHL compared with other antiviral agent with the lower percentage of adverse effect, and further study for its effect on other oral lesion may be recommended.https://rden.mosuljournals.com/pdf_9108_078c0f9f63f6b81fa5a03a4ec3f14f43.htmlrhlantiviral effect of curcumineanti inflammatory effect of curcumine
spellingShingle Maha T Al–Saffar
Comparison of New Topical Treatment (Curcumine viscous solution 30% ) For Recurrent Herpes Labialis (RHL)
Al-Rafidain Dental Journal
rhl
antiviral effect of curcumine
anti inflammatory effect of curcumine
title Comparison of New Topical Treatment (Curcumine viscous solution 30% ) For Recurrent Herpes Labialis (RHL)
title_full Comparison of New Topical Treatment (Curcumine viscous solution 30% ) For Recurrent Herpes Labialis (RHL)
title_fullStr Comparison of New Topical Treatment (Curcumine viscous solution 30% ) For Recurrent Herpes Labialis (RHL)
title_full_unstemmed Comparison of New Topical Treatment (Curcumine viscous solution 30% ) For Recurrent Herpes Labialis (RHL)
title_short Comparison of New Topical Treatment (Curcumine viscous solution 30% ) For Recurrent Herpes Labialis (RHL)
title_sort comparison of new topical treatment curcumine viscous solution 30 for recurrent herpes labialis rhl
topic rhl
antiviral effect of curcumine
anti inflammatory effect of curcumine
url https://rden.mosuljournals.com/pdf_9108_078c0f9f63f6b81fa5a03a4ec3f14f43.html
work_keys_str_mv AT mahatalsaffar comparisonofnewtopicaltreatmentcurcumineviscoussolution30forrecurrentherpeslabialisrhl