Comparison of Umbilical Cord Cleansing Using Sterile Water and Povidine Iodine-Spirit During Early Neonatal Period: A Double Blind Randomized Control Trial

Aim: To compare the effect of umbilical cord care with Povidine Iodine- Spirit on umbilical infection in early neonatal period. Materials and Methods: Prospective double blinded randomized controlled study was undertaken to evaluate the effect of daily cleansing of the umbilical cord of term inf...

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Main Authors: Gautam Chawla, K.K. Diwakar
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-07-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/6162/13562_CE(RA1)_F(T)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf
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author Gautam Chawla
K.K. Diwakar
author_facet Gautam Chawla
K.K. Diwakar
author_sort Gautam Chawla
collection DOAJ
description Aim: To compare the effect of umbilical cord care with Povidine Iodine- Spirit on umbilical infection in early neonatal period. Materials and Methods: Prospective double blinded randomized controlled study was undertaken to evaluate the effect of daily cleansing of the umbilical cord of term infants with Spirit (Alcohol) –Povidine Iodine combination). This was also compared to the retrospective data obtained for the prevailing practice of keeping the umbilical cord dry. Results: 1518 infants were included in the study. (462 in the “cord care group”, 496 in the “water” placebo group, & 560 in “Dry” retrospective group). There was an overall reduction in the clinically screened and evaluated “umbilical infection” in the Povidine –Iodine group. This was attributable to a greater reduction in the mixed bacterial (Colonizer/ commensals) isolates. The Relative Risk for Staph. aureus was lesser when the cord was kept dry (RR 0.6, p<0.01) and sterile water (Placebo) group (RR 0.7, p<0.01). Conclusion: Avoiding the antiseptic cleansing increased the RR for commensal / mixed bacterial over growth that would probably facilitate umbilical cord separation.
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spelling doaj.art-658355751c334fcbbcead013044c1bcf2022-12-22T01:58:14ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-07-0197SC01SC0310.7860/JCDR/2015/13562.6162Comparison of Umbilical Cord Cleansing Using Sterile Water and Povidine Iodine-Spirit During Early Neonatal Period: A Double Blind Randomized Control TrialGautam Chawla0K.K. Diwakar1Former Senior Resident, Department of Neonatology, Malankara Orthodox Syrian Church Medical College, Kolenchery PO, Kochi, Kerala, India.Professor & Head, Department of Neonatology, Malankara Orthodox Syrian Church Medical College, Kolenchery PO, Kochi, Kerala, India.Aim: To compare the effect of umbilical cord care with Povidine Iodine- Spirit on umbilical infection in early neonatal period. Materials and Methods: Prospective double blinded randomized controlled study was undertaken to evaluate the effect of daily cleansing of the umbilical cord of term infants with Spirit (Alcohol) –Povidine Iodine combination). This was also compared to the retrospective data obtained for the prevailing practice of keeping the umbilical cord dry. Results: 1518 infants were included in the study. (462 in the “cord care group”, 496 in the “water” placebo group, & 560 in “Dry” retrospective group). There was an overall reduction in the clinically screened and evaluated “umbilical infection” in the Povidine –Iodine group. This was attributable to a greater reduction in the mixed bacterial (Colonizer/ commensals) isolates. The Relative Risk for Staph. aureus was lesser when the cord was kept dry (RR 0.6, p<0.01) and sterile water (Placebo) group (RR 0.7, p<0.01). Conclusion: Avoiding the antiseptic cleansing increased the RR for commensal / mixed bacterial over growth that would probably facilitate umbilical cord separation.https://jcdr.net/articles/PDF/6162/13562_CE(RA1)_F(T)_PF1(PAK)_PFA(AK)_PF2(PAG).pdfumbilical careomphalitis
spellingShingle Gautam Chawla
K.K. Diwakar
Comparison of Umbilical Cord Cleansing Using Sterile Water and Povidine Iodine-Spirit During Early Neonatal Period: A Double Blind Randomized Control Trial
Journal of Clinical and Diagnostic Research
umbilical care
omphalitis
title Comparison of Umbilical Cord Cleansing Using Sterile Water and Povidine Iodine-Spirit During Early Neonatal Period: A Double Blind Randomized Control Trial
title_full Comparison of Umbilical Cord Cleansing Using Sterile Water and Povidine Iodine-Spirit During Early Neonatal Period: A Double Blind Randomized Control Trial
title_fullStr Comparison of Umbilical Cord Cleansing Using Sterile Water and Povidine Iodine-Spirit During Early Neonatal Period: A Double Blind Randomized Control Trial
title_full_unstemmed Comparison of Umbilical Cord Cleansing Using Sterile Water and Povidine Iodine-Spirit During Early Neonatal Period: A Double Blind Randomized Control Trial
title_short Comparison of Umbilical Cord Cleansing Using Sterile Water and Povidine Iodine-Spirit During Early Neonatal Period: A Double Blind Randomized Control Trial
title_sort comparison of umbilical cord cleansing using sterile water and povidine iodine spirit during early neonatal period a double blind randomized control trial
topic umbilical care
omphalitis
url https://jcdr.net/articles/PDF/6162/13562_CE(RA1)_F(T)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf
work_keys_str_mv AT gautamchawla comparisonofumbilicalcordcleansingusingsterilewaterandpovidineiodinespiritduringearlyneonatalperiodadoubleblindrandomizedcontroltrial
AT kkdiwakar comparisonofumbilicalcordcleansingusingsterilewaterandpovidineiodinespiritduringearlyneonatalperiodadoubleblindrandomizedcontroltrial