Experimental Evaluation of <sup>65</sup>Zn Decorporation Kinetics Following Rapid and Delayed Zn-DTPA Interventions in Rats. Biphasic Compartmental and Square-Root Law Mathematical Modeling

Experimental Evaluation of <sup>65</sup>Zn Decorporation Kinetics Following Rapid and Delayed Zn-DTPA Interventions in Rats. Biphasic Compartmental and Square-Root Law Mathematical Modeling

The decorporation kinetics of internal radionuclide contamination is a long-term treatment raising modeling, planning, and managing problems, especially in the case of late intervention when the radiotoxic penetrated the deep compartments. The decorporation effectiveness of the highly radiotoxic <...

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Bibliographic Details
Main Authors: Victor Voicu, Marilena Jiquidi, Constantin Mircioiu, Roxana Sandulovici, Adrian Nicolescu
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceutics
Subjects:
radionuclides
kinetics of decorporation
compartmental vs. diffusional models
square-root law
Online Access:https://www.mdpi.com/1999-4923/13/11/1830

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