Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months
Purpose: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants <6 months of age. Methods: This was a retrospective observational study conducted at a tertiary eye care center in South India. Infants under 6 months meeting the selection...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=8;spage=1088;epage=1093;aulast=Negalur |
| _version_ | 1819232057019072512 |
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| author | Mithila Negalur Virender Sachdeva Srividya Neriyanuri Mohammed Hasnat Ali Ramesh Kekunnaya |
| author_facet | Mithila Negalur Virender Sachdeva Srividya Neriyanuri Mohammed Hasnat Ali Ramesh Kekunnaya |
| author_sort | Mithila Negalur |
| collection | DOAJ |
| description | Purpose: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants <6 months of age. Methods: This was a retrospective observational study conducted at a tertiary eye care center in South India. Infants under 6 months meeting the selection criteria who underwent cataract surgery (lens aspiration, primary posterior capsulorhexis, and anterior vitrectomy) with primary IOL implantation between January 2008 and December 2011 and minimum 3-year follow-up were included. Patient demographics, serial refractions, visual acuity, complications, and associated amblyopia/strabismus were reviewed. Visual acuity, myopic shift, and complications were the outcome measures. Results: Sixty-nine eyes of 38 infants (31 bilateral; mean age: 4.6 months) were reviewed. Mean follow-up was 51 months (range: 36–84). Median logMAR best-corrected visual acuity at the final visit was 0.74 (interquartile range [IQR]: 0.50–0.98) in eyes with bilateral cataracts and 0.87 (IQR: 0.60–1.14) in eyes with unilateral cataracts with an average myopic shift of 6.7 diopters over 4.2 years. Most common postoperative complication was visual axis opacification (VAO) (13 eyes, 18%), necessitating membranectomy followed by pigmentary IOL deposits (11 eyes, 15%), and IOL decentration and glaucoma in four eyes each (5.6%). Mixed linear effect model found no significant association of age, gender, laterality, and postoperative complications with final visual acuity (P ≥ 0.05). Eyes with unilateral cataracts had a greater myopic shift than bilateral cases (P = 0.03). Conclusion: Primary IOL implantation in infants <6 months is reasonably safe in appropriately selected infants. VAO was the most common postoperative complication, and a large myopic shift was observed. |
| first_indexed | 2024-12-23T11:54:48Z |
| format | Article |
| id | doaj.art-658420f313c04eada95cd5feadc7cbb6 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-23T11:54:48Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-658420f313c04eada95cd5feadc7cbb62022-12-21T17:48:07ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892018-01-016681088109310.4103/ijo.IJO_182_18Long-term outcomes following primary intraocular lens implantation in infants younger than 6 monthsMithila NegalurVirender SachdevaSrividya NeriyanuriMohammed Hasnat AliRamesh KekunnayaPurpose: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants <6 months of age. Methods: This was a retrospective observational study conducted at a tertiary eye care center in South India. Infants under 6 months meeting the selection criteria who underwent cataract surgery (lens aspiration, primary posterior capsulorhexis, and anterior vitrectomy) with primary IOL implantation between January 2008 and December 2011 and minimum 3-year follow-up were included. Patient demographics, serial refractions, visual acuity, complications, and associated amblyopia/strabismus were reviewed. Visual acuity, myopic shift, and complications were the outcome measures. Results: Sixty-nine eyes of 38 infants (31 bilateral; mean age: 4.6 months) were reviewed. Mean follow-up was 51 months (range: 36–84). Median logMAR best-corrected visual acuity at the final visit was 0.74 (interquartile range [IQR]: 0.50–0.98) in eyes with bilateral cataracts and 0.87 (IQR: 0.60–1.14) in eyes with unilateral cataracts with an average myopic shift of 6.7 diopters over 4.2 years. Most common postoperative complication was visual axis opacification (VAO) (13 eyes, 18%), necessitating membranectomy followed by pigmentary IOL deposits (11 eyes, 15%), and IOL decentration and glaucoma in four eyes each (5.6%). Mixed linear effect model found no significant association of age, gender, laterality, and postoperative complications with final visual acuity (P ≥ 0.05). Eyes with unilateral cataracts had a greater myopic shift than bilateral cases (P = 0.03). Conclusion: Primary IOL implantation in infants <6 months is reasonably safe in appropriately selected infants. VAO was the most common postoperative complication, and a large myopic shift was observed.http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=8;spage=1088;epage=1093;aulast=NegalurComplicationsglaucomainfantsprimary Intraocular lens implantationvisual axis opacification |
| spellingShingle | Mithila Negalur Virender Sachdeva Srividya Neriyanuri Mohammed Hasnat Ali Ramesh Kekunnaya Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months Indian Journal of Ophthalmology Complications glaucoma infants primary Intraocular lens implantation visual axis opacification |
| title | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
| title_full | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
| title_fullStr | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
| title_full_unstemmed | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
| title_short | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
| title_sort | long term outcomes following primary intraocular lens implantation in infants younger than 6 months |
| topic | Complications glaucoma infants primary Intraocular lens implantation visual axis opacification |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=8;spage=1088;epage=1093;aulast=Negalur |
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