Insulin-like peptide 3 (INSL3) in congenital hypogonadotrophic hypogonadism (CHH) in boys with delayed puberty and adult men

BackgroundDelayed puberty in males is almost invariably associated with constitutional delay of growth and puberty (CDGP) or congenital hypogonadotrophic hypogonadism (CHH). Establishing the cause at presentation is challenging, with “red flag” features of CHH commonly overlooked. Thus, several mark...

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Main Authors: Ali Abbara, Kanyada Koysombat, Maria Phylactou, Pei Chia Eng, Sophie Clarke, Alexander N. Comninos, Lisa Yang, Chioma Izzi-Engbeaya, Simon Hanassab, Neil Smith, Channa N. Jayasena, Cheng Xu, Richard Quinton, Nelly Pitteloud, Gerhard Binder, Ravinder Anand-Ivell, Richard Ivell, Waljit S. Dhillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1076984/full