Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study
Alcohol use confers risk for suicidal thoughts and behaviors (ideation, attempt) in early adolescents. The Research Domain Criteria provides a framework for examination of multidimensional and modifiable risk factors. We examined distinct latent profiles based on patterns of positive valence (reward...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/12/7/935 |
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| author | Laika D. Aguinaldo Clarisa Coronado Diego A. Gomes Kelly E. Courtney Joanna Jacobus |
| author_facet | Laika D. Aguinaldo Clarisa Coronado Diego A. Gomes Kelly E. Courtney Joanna Jacobus |
| author_sort | Laika D. Aguinaldo |
| collection | DOAJ |
| description | Alcohol use confers risk for suicidal thoughts and behaviors (ideation, attempt) in early adolescents. The Research Domain Criteria provides a framework for examination of multidimensional and modifiable risk factors. We examined distinct latent profiles based on patterns of positive valence (reward responsivity) and cognitive systems (neurocognition) from the ABCD Study (age 9–10, <i>N</i> = 10,414) at baseline enrollment. Longitudinal associations were determined between baseline positive valence and cognitive profiles and group classification (alcohol use, suicidal thoughts and behaviors, or their co-occurrence) two-years after initial assessment (ages 11–12). Three unique profiles of positive valence, cognition, alcohol use, and suicidal thoughts and behaviors were identified. Two baseline profiles predicted alcohol use and suicidal thoughts and behaviors, two-years after initial assessment. Low positive valence with high cognition (but low impulsivity) predicted alcohol use (OR = 1.414, <i>p</i>< 0.001), while high positive valence with low cognition (but high impulsivity) predicted suicidal thoughts and behaviors (OR = 1.25, <i>p</i> = 0.038), compared to average positive valence and cognition. Unique profiles of positive valence and cognitive systems among 9–12-year-olds may be predictive of alcohol use and suicidal thoughts and behaviors over a two-year period. Findings underscore the potential for trajectory research on positive valence and cognitive profiles to enhance prevention for early-adolescents. |
| first_indexed | 2024-03-09T03:37:29Z |
| format | Article |
| id | doaj.art-658c2db939d647c7b40fea21e71c8f11 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-09T03:37:29Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-658c2db939d647c7b40fea21e71c8f112023-12-03T14:45:29ZengMDPI AGBrain Sciences2076-34252022-07-0112793510.3390/brainsci12070935Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) StudyLaika D. Aguinaldo0Clarisa Coronado1Diego A. Gomes2Kelly E. Courtney3Joanna Jacobus4Department of Psychiatry, University of California, La Jolla, CA 92093, USADepartment of Psychiatry, University of California, La Jolla, CA 92093, USADepartment of Psychiatry, University of California, La Jolla, CA 92093, USADepartment of Psychiatry, University of California, La Jolla, CA 92093, USADepartment of Psychiatry, University of California, La Jolla, CA 92093, USAAlcohol use confers risk for suicidal thoughts and behaviors (ideation, attempt) in early adolescents. The Research Domain Criteria provides a framework for examination of multidimensional and modifiable risk factors. We examined distinct latent profiles based on patterns of positive valence (reward responsivity) and cognitive systems (neurocognition) from the ABCD Study (age 9–10, <i>N</i> = 10,414) at baseline enrollment. Longitudinal associations were determined between baseline positive valence and cognitive profiles and group classification (alcohol use, suicidal thoughts and behaviors, or their co-occurrence) two-years after initial assessment (ages 11–12). Three unique profiles of positive valence, cognition, alcohol use, and suicidal thoughts and behaviors were identified. Two baseline profiles predicted alcohol use and suicidal thoughts and behaviors, two-years after initial assessment. Low positive valence with high cognition (but low impulsivity) predicted alcohol use (OR = 1.414, <i>p</i>< 0.001), while high positive valence with low cognition (but high impulsivity) predicted suicidal thoughts and behaviors (OR = 1.25, <i>p</i> = 0.038), compared to average positive valence and cognition. Unique profiles of positive valence and cognitive systems among 9–12-year-olds may be predictive of alcohol use and suicidal thoughts and behaviors over a two-year period. Findings underscore the potential for trajectory research on positive valence and cognitive profiles to enhance prevention for early-adolescents.https://www.mdpi.com/2076-3425/12/7/935RDoCsuicide preventionsuicide interventionpre-teen youthalcohol use |
| spellingShingle | Laika D. Aguinaldo Clarisa Coronado Diego A. Gomes Kelly E. Courtney Joanna Jacobus Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study Brain Sciences RDoC suicide prevention suicide intervention pre-teen youth alcohol use |
| title | Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study |
| title_full | Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study |
| title_fullStr | Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study |
| title_full_unstemmed | Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study |
| title_short | Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study |
| title_sort | application of the rdoc framework to predict alcohol use and suicidal thoughts and behaviors among early adolescents in the adolescent brain and cognitive development abcd study |
| topic | RDoC suicide prevention suicide intervention pre-teen youth alcohol use |
| url | https://www.mdpi.com/2076-3425/12/7/935 |
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