I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT

It is known, transplantation of organs is accompanied by activation of adaptive immunity (cellular and humoral) and innate immunity in an organism of the recipient. Population of T-lymphocyte which includes some subpopu- lations of cells , such as Тcyt, Th1, Th2 and T-regulatory cells, first of all...

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Main Authors: S. D. Artamonov, N. A. Onishchenko, L. V. Bashkina, V. S. Suskova, M. E. Krasheninnikov, A. O. Nikol’skaya, D. A. Velikiy
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2010-06-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/335
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author S. D. Artamonov
N. A. Onishchenko
L. V. Bashkina
V. S. Suskova
M. E. Krasheninnikov
A. O. Nikol’skaya
D. A. Velikiy
author_facet S. D. Artamonov
N. A. Onishchenko
L. V. Bashkina
V. S. Suskova
M. E. Krasheninnikov
A. O. Nikol’skaya
D. A. Velikiy
author_sort S. D. Artamonov
collection DOAJ
description It is known, transplantation of organs is accompanied by activation of adaptive immunity (cellular and humoral) and innate immunity in an organism of the recipient. Population of T-lymphocyte which includes some subpopu- lations of cells , such as Тcyt, Th1, Th2 and T-regulatory cells, first of all responsible for development of these forms of the immune answer. The actual problem of modern transplantology is working out of methods which would promote accumulation in an organism of recipient T-regulatory of cells with suppressive properties for formation the donor-specific immune tolerance into recipient`s organism.
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spelling doaj.art-658e720802c14888a1da152b556a4ce42023-03-13T10:37:20ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912010-06-0112311212010.15825/1995-1191-2010-3-112-120278I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFTS. D. Artamonov0N. A. Onishchenko1L. V. Bashkina2V. S. Suskova3M. E. Krasheninnikov4A. O. Nikol’skaya5D. A. Velikiy6Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowIt is known, transplantation of organs is accompanied by activation of adaptive immunity (cellular and humoral) and innate immunity in an organism of the recipient. Population of T-lymphocyte which includes some subpopu- lations of cells , such as Тcyt, Th1, Th2 and T-regulatory cells, first of all responsible for development of these forms of the immune answer. The actual problem of modern transplantology is working out of methods which would promote accumulation in an organism of recipient T-regulatory of cells with suppressive properties for formation the donor-specific immune tolerance into recipient`s organism.https://journal.transpl.ru/vtio/article/view/335innate immunityadaptive immunityorgan transplantationt-regulatory cellstransplantation tolerance.
spellingShingle S. D. Artamonov
N. A. Onishchenko
L. V. Bashkina
V. S. Suskova
M. E. Krasheninnikov
A. O. Nikol’skaya
D. A. Velikiy
I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT
Vestnik Transplantologii i Iskusstvennyh Organov
innate immunity
adaptive immunity
organ transplantation
t-regulatory cells
transplantation tolerance.
title I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT
title_full I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT
title_fullStr I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT
title_full_unstemmed I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT
title_short I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT
title_sort i role of the innate and adaptive immunity for a development of destructive immune response of organism on allograft
topic innate immunity
adaptive immunity
organ transplantation
t-regulatory cells
transplantation tolerance.
url https://journal.transpl.ru/vtio/article/view/335
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