Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sample
UV/Vis absorption spectroelectrochemistry (SEC) is a multi-response technique that has been commonly used for the characterization of materials and the study of reaction mechanisms. However, it has been scarcely used for quantitative purposes. SEC allows us to obtain two analytical signals simultane...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/18/5179 |
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| author | Fabiola Olmo Jesus Garoz-Ruiz Julia Carazo Alvaro Colina Aranzazu Heras |
| author_facet | Fabiola Olmo Jesus Garoz-Ruiz Julia Carazo Alvaro Colina Aranzazu Heras |
| author_sort | Fabiola Olmo |
| collection | DOAJ |
| description | UV/Vis absorption spectroelectrochemistry (SEC) is a multi-response technique that has been commonly used for the characterization of materials and the study of reaction mechanisms. However, it has been scarcely used for quantitative purposes. SEC allows us to obtain two analytical signals simultaneously, yielding a dual sensor in just one experiment. In the last years, our group has developed new devices useful for analysis. In this work, a SEC device in parallel configuration, based on optical fibers fixed on screen-printed electrodes, was used to determine isoprenaline in a commercial drug, using both, the electrochemical and the spectroscopic signals. In this commercial drug, isoprenaline is accompanied in solution by other compounds. Among them is sodium metabisulfite, an antioxidant that strongly interferes in the isoprenaline determination. A simple pretreatment of the drug sample by bubbling wet-air allows us to avoid the interference of metabisulfite. Here, we demonstrate again the capabilities of UV/Vis absorption SEC as double sensor for analysis and we propose a simple pretreatment to remove interfering compounds. |
| first_indexed | 2024-03-10T16:24:26Z |
| format | Article |
| id | doaj.art-65957f3959394312ba1e5b9189a1d4ad |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T16:24:26Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-65957f3959394312ba1e5b9189a1d4ad2023-11-20T13:20:17ZengMDPI AGSensors1424-82202020-09-012018517910.3390/s20185179Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical SampleFabiola Olmo0Jesus Garoz-Ruiz1Julia Carazo2Alvaro Colina3Aranzazu Heras4Department of Chemistry, Universidad de Burgos, Pza. Misael Bañuelos s/n, E-09001 Burgos, SpainDepartment of Chemistry, Universidad de Burgos, Pza. Misael Bañuelos s/n, E-09001 Burgos, SpainDepartment of Chemistry, Universidad de Burgos, Pza. Misael Bañuelos s/n, E-09001 Burgos, SpainDepartment of Chemistry, Universidad de Burgos, Pza. Misael Bañuelos s/n, E-09001 Burgos, SpainDepartment of Chemistry, Universidad de Burgos, Pza. Misael Bañuelos s/n, E-09001 Burgos, SpainUV/Vis absorption spectroelectrochemistry (SEC) is a multi-response technique that has been commonly used for the characterization of materials and the study of reaction mechanisms. However, it has been scarcely used for quantitative purposes. SEC allows us to obtain two analytical signals simultaneously, yielding a dual sensor in just one experiment. In the last years, our group has developed new devices useful for analysis. In this work, a SEC device in parallel configuration, based on optical fibers fixed on screen-printed electrodes, was used to determine isoprenaline in a commercial drug, using both, the electrochemical and the spectroscopic signals. In this commercial drug, isoprenaline is accompanied in solution by other compounds. Among them is sodium metabisulfite, an antioxidant that strongly interferes in the isoprenaline determination. A simple pretreatment of the drug sample by bubbling wet-air allows us to avoid the interference of metabisulfite. Here, we demonstrate again the capabilities of UV/Vis absorption SEC as double sensor for analysis and we propose a simple pretreatment to remove interfering compounds.https://www.mdpi.com/1424-8220/20/18/5179spectroelectrochemistryelectrochemistryUV/Vis absorptiondrug analysisisoproterenolmetabisulfite |
| spellingShingle | Fabiola Olmo Jesus Garoz-Ruiz Julia Carazo Alvaro Colina Aranzazu Heras Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sample Sensors spectroelectrochemistry electrochemistry UV/Vis absorption drug analysis isoproterenol metabisulfite |
| title | Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sample |
| title_full | Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sample |
| title_fullStr | Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sample |
| title_full_unstemmed | Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sample |
| title_short | Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sample |
| title_sort | spectroelectrochemical determination of isoprenaline in a pharmaceutical sample |
| topic | spectroelectrochemistry electrochemistry UV/Vis absorption drug analysis isoproterenol metabisulfite |
| url | https://www.mdpi.com/1424-8220/20/18/5179 |
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