A phase I trial of cyclosporine for hospitalized patients with COVID-19
BACKGROUND COVID-19 remains a global health emergency with limited treatment options, lagging vaccine rates, and inadequate healthcare resources in the face of an ongoing calamity. The disease is characterized by immune dysregulation and cytokine storm. Cyclosporine A (CSA) is a calcineurin inhibito...
Main Authors: | Emily A. Blumberg, Julia Han Noll, Pablo Tebas, Joseph A. Fraietta, Ian Frank, Amy Marshall, Anne Chew, Elizabeth A. Veloso, Alison Carulli, Walter Rogal, Avery L. Gaymon, Aliza H. Schmidt, Tiffany Barnette, Renee Jurek, Rene Martins, Briana M. Hudson, Kalyan Chavda, Christina M. Bailey, Sarah E. Church, Hooman Noorchashm, Wei-Ting Hwang, Carl H. June, Elizabeth O. Hexner |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2022-06-01
|
Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.155682 |
Similar Items
-
Cyclosporine
by: Russell, N, et al.
Published: (2008) -
Cyclosporine
by: Nahide Onsun
Published: (2022-04-01) -
The controversial early history of cyclosporin
by: K Heusler, et al.
Published: (2001-06-01) -
Structure of Cyclosporine and Its Metabolites: Total Synthesis of Cyclosporine Metabolites Formed by Oxidation at Positions 4 and 9 of Cyclosporine. Preparation of Leucine-4-cyclosporine, (?-Hydroxy)-N-methyl-leucine-9-cyclosporine and Leucine-4-(?-hydroxy)-N-methyl-leucine-9-cyclosporine
by: Roland M. Wenger, et al.
Published: (1992-07-01) -
Efficacy and Safety of 0.1% Cyclosporine versus 2% Cyclosporine in the Treatment of Severe Vernal Keratoconjunctivitis in Children
by: Bourcier T, et al.
Published: (2022-10-01)