Diagnostic Value of Frozen Section in Endometrial Curetting Compared to Permanent Pathology
Background: Frozen section is widely used in gynecological oncology. However, the accuracy of frozen section procedure in intraoperative diagnosis of endometrial hyperplasia and endometrial adenocarcinoma in endometrial curettings has not been studied. The aim of this study was determining the accur...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2011-03-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/853 |
| _version_ | 1827838717660758016 |
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| author | Azar Danesh Shahraki Sheida Shabanian Borujeni Fereshteh Mohammadizadeh Bahram Khorram Tajossadat Allameh |
| author_facet | Azar Danesh Shahraki Sheida Shabanian Borujeni Fereshteh Mohammadizadeh Bahram Khorram Tajossadat Allameh |
| author_sort | Azar Danesh Shahraki |
| collection | DOAJ |
| description | Background: Frozen section is widely used in gynecological oncology. However, the accuracy of frozen section procedure in intraoperative diagnosis of endometrial hyperplasia and endometrial adenocarcinoma in endometrial curettings has not been studied. The aim of this study was determining the accuracy of frozen section in evaluation of histopathologic findings of endometrial curettings from peri- and postmenopausal women with abnormal uterine bleeding (AUB).
Methods: 71 women having 45 years or more with the complaint of AUB entered the study. In pathology lab, part of fresh diagnostic sample was prepared for frozen section and the remainder was fixed and further processed for permanent pathology. Permanent pathology was considered as the gold standard for evaluation of histopathologic findings. χ2 and Fisher’s exact tests were used for statistical analysis.
Finding: The findings of frozen section were exactly the same as permanent pathology in 70 persent of patients. Despite high specificity of frozen section in detecting various histopathologic findings, significant statistical difference was seen between frozen section and permanent pathology in all of these findings.
Conclusion: Our results are in favor of the superiority of permanent pathology over frozen section in evaluation of endometrial curettings. However, according to high specificity of frozen section examination in detecting endometrial hyperplasia and adenocarcinoma, it may be acceptable to rely on the results of frozen section in these conditions to make an intraoperative decision for the type and extent of surgery. |
| first_indexed | 2024-03-12T07:10:11Z |
| format | Article |
| id | doaj.art-65982ffaa97742389bdb2bc56c4cc7dc |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T07:10:11Z |
| publishDate | 2011-03-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-65982ffaa97742389bdb2bc56c4cc7dc2023-09-02T23:11:18ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2011-03-012812015211528563Diagnostic Value of Frozen Section in Endometrial Curetting Compared to Permanent PathologyAzar Danesh Shahraki0Sheida Shabanian Borujeni1Fereshteh Mohammadizadeh2Bahram Khorram3Tajossadat Allameh4Associate Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranGynecologist, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, IranAssociate Professor, Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAnesthesiologist, Valie-Asr Hospital, Boroujen, IranAssociate Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranBackground: Frozen section is widely used in gynecological oncology. However, the accuracy of frozen section procedure in intraoperative diagnosis of endometrial hyperplasia and endometrial adenocarcinoma in endometrial curettings has not been studied. The aim of this study was determining the accuracy of frozen section in evaluation of histopathologic findings of endometrial curettings from peri- and postmenopausal women with abnormal uterine bleeding (AUB). Methods: 71 women having 45 years or more with the complaint of AUB entered the study. In pathology lab, part of fresh diagnostic sample was prepared for frozen section and the remainder was fixed and further processed for permanent pathology. Permanent pathology was considered as the gold standard for evaluation of histopathologic findings. χ2 and Fisher’s exact tests were used for statistical analysis. Finding: The findings of frozen section were exactly the same as permanent pathology in 70 persent of patients. Despite high specificity of frozen section in detecting various histopathologic findings, significant statistical difference was seen between frozen section and permanent pathology in all of these findings. Conclusion: Our results are in favor of the superiority of permanent pathology over frozen section in evaluation of endometrial curettings. However, according to high specificity of frozen section examination in detecting endometrial hyperplasia and adenocarcinoma, it may be acceptable to rely on the results of frozen section in these conditions to make an intraoperative decision for the type and extent of surgery.http://jims.mui.ac.ir/index.php/jims/article/view/853Abnormal uterine bleedingPostmenopauseFrozen sectionsEndometrial hyperplasiaEndometrial adenocarcinoma |
| spellingShingle | Azar Danesh Shahraki Sheida Shabanian Borujeni Fereshteh Mohammadizadeh Bahram Khorram Tajossadat Allameh Diagnostic Value of Frozen Section in Endometrial Curetting Compared to Permanent Pathology مجله دانشکده پزشکی اصفهان Abnormal uterine bleeding Postmenopause Frozen sections Endometrial hyperplasia Endometrial adenocarcinoma |
| title | Diagnostic Value of Frozen Section in Endometrial Curetting Compared to Permanent Pathology |
| title_full | Diagnostic Value of Frozen Section in Endometrial Curetting Compared to Permanent Pathology |
| title_fullStr | Diagnostic Value of Frozen Section in Endometrial Curetting Compared to Permanent Pathology |
| title_full_unstemmed | Diagnostic Value of Frozen Section in Endometrial Curetting Compared to Permanent Pathology |
| title_short | Diagnostic Value of Frozen Section in Endometrial Curetting Compared to Permanent Pathology |
| title_sort | diagnostic value of frozen section in endometrial curetting compared to permanent pathology |
| topic | Abnormal uterine bleeding Postmenopause Frozen sections Endometrial hyperplasia Endometrial adenocarcinoma |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/853 |
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