The Activity of Natural Polymorphic Variants of Human DNA Polymerase β Having an Amino Acid Substitution in the Transferase Domain

To maintain the integrity of the genome, there is a set of enzymatic systems, one of which is base excision repair (BER), which includes sequential action of DNA glycosylases, apurinic/apyrimidinic endonucleases, DNA polymerases, and DNA ligases. Normally, BER works efficiently, but the enzymes them...

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Hlavní autoři: Olga A. Kladova, Timofey E. Tyugashev, Elena S. Mikushina, Nikita A. Kuznetsov, Daria S. Novopashina, Aleksandra A. Kuznetsova
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2023-05-01
Edice:Cells
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On-line přístup:https://www.mdpi.com/2073-4409/12/9/1300