New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease
Chronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-05-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/5/2/74 |
| _version_ | 1827717219164880896 |
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| author | Renata J. Moll-Bernardes Paulo Henrique Rosado-de-Castro Gabriel Cordeiro Camargo Fernanda Souza Nogueira Sardinha Mendes Adriana S. X. Brito Andréa Silvestre Sousa |
| author_facet | Renata J. Moll-Bernardes Paulo Henrique Rosado-de-Castro Gabriel Cordeiro Camargo Fernanda Souza Nogueira Sardinha Mendes Adriana S. X. Brito Andréa Silvestre Sousa |
| author_sort | Renata J. Moll-Bernardes |
| collection | DOAJ |
| description | Chronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of myocardial fibrosis, inflammation or sympathetic denervation, three conditions associated with risk of sudden death, providing additional diagnostic and/or prognostic information. Unfortunately, despite its high mortality, there is no clear recommendation for early cardioverter-defibrillator implantation in patients with Chagas heart disease in the current guidelines. Ideally, the risk of sudden cardiac death may be evaluated in earlier stages of the disease using new image methods to allow the implementation of primary preventive strategies. |
| first_indexed | 2024-03-10T19:57:26Z |
| format | Article |
| id | doaj.art-65a02e35c847475a85aab528f1498440 |
| institution | Directory Open Access Journal |
| issn | 2414-6366 |
| language | English |
| last_indexed | 2024-03-10T19:57:26Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj.art-65a02e35c847475a85aab528f14984402023-11-19T23:48:49ZengMDPI AGTropical Medicine and Infectious Disease2414-63662020-05-01527410.3390/tropicalmed5020074New Imaging Parameters to Predict Sudden Cardiac Death in Chagas DiseaseRenata J. Moll-Bernardes0Paulo Henrique Rosado-de-Castro1Gabriel Cordeiro Camargo2Fernanda Souza Nogueira Sardinha Mendes3Adriana S. X. Brito4Andréa Silvestre Sousa5D’Or Institute for Research and Education (IDOR), Rio de Janeiro 22281-100, BrazilD’Or Institute for Research and Education (IDOR), Rio de Janeiro 22281-100, BrazilD’Or Institute for Research and Education (IDOR), Rio de Janeiro 22281-100, BrazilEvandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, BrazilD’Or Institute for Research and Education (IDOR), Rio de Janeiro 22281-100, BrazilD’Or Institute for Research and Education (IDOR), Rio de Janeiro 22281-100, BrazilChronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of myocardial fibrosis, inflammation or sympathetic denervation, three conditions associated with risk of sudden death, providing additional diagnostic and/or prognostic information. Unfortunately, despite its high mortality, there is no clear recommendation for early cardioverter-defibrillator implantation in patients with Chagas heart disease in the current guidelines. Ideally, the risk of sudden cardiac death may be evaluated in earlier stages of the disease using new image methods to allow the implementation of primary preventive strategies.https://www.mdpi.com/2414-6366/5/2/74Chagas diseasecardiomyopathymyocardial fibrosismyocardial sympathetic denervationinflammationsudden death |
| spellingShingle | Renata J. Moll-Bernardes Paulo Henrique Rosado-de-Castro Gabriel Cordeiro Camargo Fernanda Souza Nogueira Sardinha Mendes Adriana S. X. Brito Andréa Silvestre Sousa New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease Tropical Medicine and Infectious Disease Chagas disease cardiomyopathy myocardial fibrosis myocardial sympathetic denervation inflammation sudden death |
| title | New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease |
| title_full | New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease |
| title_fullStr | New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease |
| title_full_unstemmed | New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease |
| title_short | New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease |
| title_sort | new imaging parameters to predict sudden cardiac death in chagas disease |
| topic | Chagas disease cardiomyopathy myocardial fibrosis myocardial sympathetic denervation inflammation sudden death |
| url | https://www.mdpi.com/2414-6366/5/2/74 |
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