Novel MEIOB variants cause primary ovarian insufficiency and non-obstructive azoospermia

Novel MEIOB variants cause primary ovarian insufficiency and non-obstructive azoospermia

Background: Infertility is a global health concern. MEIOB has been found to be associated with premature ovarian insufficiency (POI) and non-obstructive azoospermia (NOA), but its variants have not been reported in Chinese patients. The aim of this study was to identify the genetic aetiology of POI...

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Bibliographic Details
Main Authors: Yurong Wang, Ling Liu, Chen Tan, Guiquan Meng, Lanlan Meng, Hongchuan Nie, Juan Du, Guang-Xiu Lu, Ge Lin, Wen-Bin He, Yue-Qiu Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
primary ovarian insufficiency
non-obstructive azoospermia
MEIOB gene
novel variant
immunofluorescence
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.936264/full

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