Smyd1b_tv1, a key regulator of sarcomere assembly, is localized on the M-line of skeletal muscle fibers.

BACKGROUND:Smyd1b is a member of the Smyd family that plays a key role in sarcomere assembly during myofibrillogenesis. Smyd1b encodes two alternatively spliced isoforms, smyd1b_tv1 and smyd1b_tv2, that are expressed in skeletal and cardiac muscles and play a vital role in myofibrillogenesis in skel...

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Bibliographic Details
Main Authors: Huiqing Li, Jin Xu, Yue-Hong Bian, Pep Rotllant, Tiansheng Shen, Wuying Chu, Jianshe Zhang, Martin Schneider, Shao Jun Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3235123?pdf=render