Lymphocyte-Activation Gene 3 (LAG3) Protein as a Possible Therapeutic Target for Parkinson’s Disease: Molecular Mechanisms Connecting Neuroinflammation to α-Synuclein Spreading Pathology

Lymphocyte-Activation Gene 3 (LAG3) Protein as a Possible Therapeutic Target for Parkinson’s Disease: Molecular Mechanisms Connecting Neuroinflammation to α-Synuclein Spreading Pathology

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder without any objective biomarker available to date. Increasing evidence highlights the critical role of neuroinflammation, including T cell responses, and spreading of aggregated α-synuclein in PD progression. Lymphocyte-...

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Bibliographic Details
Main Authors: Efthalia Angelopoulou, Yam Nath Paudel, Chiara Villa, Mohd. Farooq Shaikh, Christina Piperi
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biology
Subjects:
LAG3
Parkinson’s disease
α-synuclein
neuroinflammation
biomarker
Online Access:https://www.mdpi.com/2079-7737/9/4/86

Internet

https://www.mdpi.com/2079-7737/9/4/86

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