Bone marrow adipocytes is a new player in supporting myeloma cells proliferation and survival in myeloma microenvironment

Bone marrow adipocytes is a new player in supporting myeloma cells proliferation and survival in myeloma microenvironment

Multiple myeloma (MM) is a lethal B cell neoplasm characterized by clonal expansion of malignant plasma cells in the bone marrow and remains incurable due to disease relapse and drug resistance. Bone marrow adipocytes (BMAs) are emerging as playing active functions that can support myeloma cell grow...

Full description

Bibliographic Details
Main Authors:	Xiaoqian Wei, Yangmin Zhang, Ziyan Wang, Yuanning He, Songguang Ju, Jinxiang Fu
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Series:	Translational Oncology
Subjects:	Multiple myeloma Myeloma associated adipocytes Mesenchymal stem cells Survival Drug resistance
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523323002425

Similar Items

Bone Marrow Mesenchymal Stromal Cells in Multiple Myeloma: Their Role as Active Contributors to Myeloma Progression
by: Patricia Maiso, et al.
Published: (2021-05-01)

Unlocking Drug Resistance in Multiple Myeloma: Adipocytes as Modulators of Treatment Response
by: Maria Ochiai, et al.
Published: (2023-08-01)

Prognostic Analysis of Socioeconomic Factors in Multiple Myeloma Patients and Construction of A Myeloma-specific Survival Prediction Model
by: XU Jiaxuan, et al.
Published: (2023-04-01)

Game of Bones: How Myeloma Manipulates Its Microenvironment
by: Tyler Moser-Katz, et al.
Published: (2021-02-01)

Development and characterization of three cell culture systems to investigate the relationship between primary bone marrow adipocytes and myeloma cells
by: Heather Fairfield, et al.
Published: (2023-01-01)

Natural History and Prognostic Factors at First Relapse in Multiple Myeloma
by: Chen Wang, et al.
Published: (2020-07-01)

Bone Marrow Adipocytes: A Link between Obesity and Bone Cancer
by: Michaela R. Reagan, et al.
Published: (2021-01-01)

EDNRA-Expressing Mesenchymal Cells Are Expanded in Myeloma Interstitial Bone Marrow and Associated with Disease Progression
by: Wen Ling, et al.
Published: (2023-09-01)

Trends in survival from myeloma, 1990–2015: a competing risks analysis
by: Mary Jane Sneyd, et al.
Published: (2021-07-01)

Induction of m6A methylation in adipocyte exosomal LncRNAs mediates myeloma drug resistance
by: Zhiming Wang, et al.
Published: (2022-01-01)

Myeloma /
by: 455001 Tanner, Jerome E., et al.
Published: (2008)

Frequency and prognostic significance of hypercalcemia in patients with multiple myeloma
by: Kanar J Karim, et al.
Published: (2020-01-01)

Effect of autoimmune diseases on incidence and survival in subsequent multiple myeloma
by: Hemminki Kari, et al.
Published: (2012-10-01)

Anaplastic morphology in IgD multiple myeloma
by: Verónica Roldán Galiacho, et al.
Published: (2023-10-01)

Bone Marrow Microenvironment Interplay and Current Clinical Practice in Multiple Myeloma: A Review of the Balkan Myeloma Study Group
by: Jelena Bila, et al.
Published: (2021-08-01)

Socioeconomic status-based survival disparities and nomogram prediction for patients with multiple myeloma: Results from American and Chinese populations
by: Jiaxuan Xu, et al.
Published: (2022-08-01)

Survival in patients with multiple myeloma: evaluation of possible associations with bone marrow fibrosis and investigation of factors independently associated with survival
by: Esma Evrim Dogan, et al.
Published: (2022-09-01)

Description of multiple myeloma cases and assessment of survival and mortality factors in Madagascar
by: Rova Malala Fandresena Randrianarisoa, et al.
Published: (2023-12-01)

High IKZF1/3 protein expression is a favorable prognostic factor for survival of relapsed/refractory multiple myeloma patients treated with lenalidomide
by: Maryam Pourabdollah, et al.
Published: (2016-11-01)

Multiple Myeloma: An Update
by: Khalil Al-Farsi
Published: (2013-01-01)

Editorial: The role of the bone marrow microenvironment in multiple myeloma evolution and therapy
by: Carolina Schinke, et al.
Published: (2023-02-01)

Young age and autologous stem cell transplantation are associated with improved survival in newly diagnosed multiple myeloma
by: Virginia Bove, et al.
Published: (2021-07-01)

Presentation and survival of multiple myeloma patients in Ghana: a review of 9 cases
by: Michael E. Acquah, et al.
Published: (2019-03-01)

Oncolytic Virotherapy and Microenvironment in Multiple Myeloma
by: Valentina Marchica, et al.
Published: (2021-02-01)

Bone Marrow Adipocytes Contribute to Tumor Microenvironment-Driven Chemoresistance via Sequestration of Doxorubicin
by: Jun-Goo Kwak, et al.
Published: (2023-05-01)

Connect MM Registry as a national reference for United States multiple myeloma patients
by: Sikander Ailawadhi, et al.
Published: (2020-01-01)

Epidemiology of multiple myeloma in city Moscow
by: O Yu Vinogradova, et al.
Published: (2019-07-01)

Bone marrow adipocytes and multiple myeloma
by: A. A. Philchenkov
Published: (2019-04-01)

Multiple myeloma and kidney disease
by: Natalia Zarankiewicz, et al.
Published: (2022-08-01)

Multiple myeloma in Armenia during the period 2006–2018: facts and discussion
by: Narine Ghazaryan, et al.
Published: (2021-08-01)

Education level as a predictor of survival in patients with multiple myeloma
by: Limei Xu, et al.
Published: (2020-08-01)

Plasmablastic myeloma progressed to plasma cell leukaemia
by: Ke Xu, et al.
Published: (2021-11-01)

Multiple myeloma presenting with coexisting severe marrow hypoplasia
by: Medhi K, et al.
Published: (2008-10-01)

Immunophenotypic Characteristics of Bone Marrow Microenvironment Cellular Composition at the Biochemical Progression of Multiple Myeloma
by: Agnieszka Krzywdzińska, et al.
Published: (2022-06-01)

Genetic Abnormalities in Extramedullary Multiple Myeloma
by: Roisin McAvera, et al.
Published: (2023-07-01)

Editorial: Molecular Mechanisms of Multiple Myeloma
by: Alessandro Gozzetti, et al.
Published: (2022-03-01)

Emerging Roles of Osteoclasts in the Modulation of Bone Microenvironment and Immune Suppression in Multiple Myeloma
by: Anna Mansour, et al.
Published: (2017-08-01)

PD-L1/PD-1 Pattern of Expression Within the Bone Marrow Immune Microenvironment in Smoldering Myeloma and Active Multiple Myeloma Patients
by: Federica Costa, et al.
Published: (2021-01-01)

Racial differences in treatment and survival among older patients with multiple myeloma
by: Rong Wang, et al.
Published: (2024-02-01)

PLASMA CELL MORPHOLOGY IN MULTIPLE MYELOMA
by: JP. Mufuta, et al.
Published: (2014-12-01)