Treatment of cardiac synovial sarcoma: experience of two cases
Abstract Background Primary heart sarcomas are exceedingly rare tumors. Among primary cardiac sarcomas, synovial sarcoma is one of the rarest, involving cardiac cavities or pericardium. Case presentation Two cases of synovial sarcoma are presented with the clinical course and therapy. Both cases wer...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-07-01
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| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13019-018-0771-0 |
| _version_ | 1828434952979480576 |
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| author | Antonella Coli Giovanni Alfonso Chiariello Mariangela Novello Christian Colizzi Massimo Massetti |
| author_facet | Antonella Coli Giovanni Alfonso Chiariello Mariangela Novello Christian Colizzi Massimo Massetti |
| author_sort | Antonella Coli |
| collection | DOAJ |
| description | Abstract Background Primary heart sarcomas are exceedingly rare tumors. Among primary cardiac sarcomas, synovial sarcoma is one of the rarest, involving cardiac cavities or pericardium. Case presentation Two cases of synovial sarcoma are presented with the clinical course and therapy. Both cases were treated with surgery and chemo/radiotherapy. Interestingly, one of the patient, a 52-year-old male with an intracardiac synovial sarcoma, undergone a SynCardia total artificial heart implantation, but died for multiple pulmonary metastases waiting for transplantation. Conclusion Complete surgical resection of cardiac synovial sarcoma is the gold standard of therapy, though rarely possible. Although guidelines for the treatment are not well established, due to limited number of cases reported, chemotherapy and radiotherapy are frequently administered and seem to prolong mean patient’s survival. Cardiac transplantation could be considered in selected cases. |
| first_indexed | 2024-12-10T18:58:17Z |
| format | Article |
| id | doaj.art-65a5264a799245b5a328b5e22d926a8d |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-12-10T18:58:17Z |
| publishDate | 2018-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-65a5264a799245b5a328b5e22d926a8d2022-12-22T01:37:04ZengBMCJournal of Cardiothoracic Surgery1749-80902018-07-011311310.1186/s13019-018-0771-0Treatment of cardiac synovial sarcoma: experience of two casesAntonella Coli0Giovanni Alfonso Chiariello1Mariangela Novello2Christian Colizzi3Massimo Massetti4Institute of Anatomic Pathology, Catholic University of Sacred HeartDepartment of Cardiovascular Sciences, Catholic University of Sacred HeartInstitute of Anatomic Pathology, Catholic University of Sacred HeartDepartment of Cardiovascular Sciences, Catholic University of Sacred HeartDepartment of Cardiovascular Sciences, Catholic University of Sacred HeartAbstract Background Primary heart sarcomas are exceedingly rare tumors. Among primary cardiac sarcomas, synovial sarcoma is one of the rarest, involving cardiac cavities or pericardium. Case presentation Two cases of synovial sarcoma are presented with the clinical course and therapy. Both cases were treated with surgery and chemo/radiotherapy. Interestingly, one of the patient, a 52-year-old male with an intracardiac synovial sarcoma, undergone a SynCardia total artificial heart implantation, but died for multiple pulmonary metastases waiting for transplantation. Conclusion Complete surgical resection of cardiac synovial sarcoma is the gold standard of therapy, though rarely possible. Although guidelines for the treatment are not well established, due to limited number of cases reported, chemotherapy and radiotherapy are frequently administered and seem to prolong mean patient’s survival. Cardiac transplantation could be considered in selected cases.http://link.springer.com/article/10.1186/s13019-018-0771-0Synovial sarcomaCardiac tumorsTherapyTotal artificial heart implantation |
| spellingShingle | Antonella Coli Giovanni Alfonso Chiariello Mariangela Novello Christian Colizzi Massimo Massetti Treatment of cardiac synovial sarcoma: experience of two cases Journal of Cardiothoracic Surgery Synovial sarcoma Cardiac tumors Therapy Total artificial heart implantation |
| title | Treatment of cardiac synovial sarcoma: experience of two cases |
| title_full | Treatment of cardiac synovial sarcoma: experience of two cases |
| title_fullStr | Treatment of cardiac synovial sarcoma: experience of two cases |
| title_full_unstemmed | Treatment of cardiac synovial sarcoma: experience of two cases |
| title_short | Treatment of cardiac synovial sarcoma: experience of two cases |
| title_sort | treatment of cardiac synovial sarcoma experience of two cases |
| topic | Synovial sarcoma Cardiac tumors Therapy Total artificial heart implantation |
| url | http://link.springer.com/article/10.1186/s13019-018-0771-0 |
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