Integrative rare disease biomedical profile based network supporting drug repurposing or repositioning, a case study of glioblastoma

Integrative rare disease biomedical profile based network supporting drug repurposing or repositioning, a case study of glioblastoma

Abstract Background Glioblastoma (GBM) is the most aggressive and common malignant primary brain tumor; however, treatment remains a significant challenge. This study aims to identify drug repurposing or repositioning candidates for GBM by developing an integrative rare disease profile network conta...

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Bibliographic Details
Main Authors: Erin McGowan, Jaleal Sanjak, Ewy A. Mathé, Qian Zhu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Data integration
Network analysis
Drug repurposing or repositioning
Glioblastoma
Online Access:https://doi.org/10.1186/s13023-023-02876-2

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