Layout optimization of the beam spot locations scanned by electromagnets in particle beam therapy
This paper presents a layout optimization method of the spot locations of pencil beam scanning for particle beam cancer therapy. With the pencil beam scanning technique, the particle beam is scanned from spot to spot in the tumor by using scanning magnets. To provide clinically ideal dose distributi...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Japan Society of Mechanical Engineers
2022-09-01
|
| Series: | Mechanical Engineering Journal |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/mej/9/5/9_22-00140/_pdf/-char/en |
| _version_ | 1797985047516545024 |
|---|---|
| author | Yusuke SAKAMOTO Takayuki NAGASHIMA Yuki SATO Kazuhiro IZUI Shinji NISHIWAKI |
| author_facet | Yusuke SAKAMOTO Takayuki NAGASHIMA Yuki SATO Kazuhiro IZUI Shinji NISHIWAKI |
| author_sort | Yusuke SAKAMOTO |
| collection | DOAJ |
| description | This paper presents a layout optimization method of the spot locations of pencil beam scanning for particle beam cancer therapy. With the pencil beam scanning technique, the particle beam is scanned from spot to spot in the tumor by using scanning magnets. To provide clinically ideal dose distributions and less-invasive treatment to the patients, both the spot locations and the number of particles given to each spot should be optimized. However, the spot layout is fixed with a lattice pattern in many prior studies. We propose the optimization method to derive the non-lattice spot layout to realize an acceptable dose distribution with a reduced number of spots. With the proposed method, a large enough number of spots were located densely at the initial state, and then the spots with the smallest contribution were removed one by one through iterations. The number of particles given to each spot was determined by solving a quadratic problem. Furthermore, we also propose the idea to accelerate the optimization process by simultaneously removing multiple spots. The algorithm was confirmed by numerical examples of both two-dimensional and three-dimensional cases. The dose quality with the optimized spot layout was better than that with the conventional lattice spot patterns, with all tested cases. In the optimized spot layout, the spots were located on the closed lines which were concentric to the target contour. We also confirmed the proposed method of multiple-remotion can accelerate the optimization process without violating the dose quality. |
| first_indexed | 2024-04-11T07:12:12Z |
| format | Article |
| id | doaj.art-65a7e5e382584abea3d69256c7f1fd1c |
| institution | Directory Open Access Journal |
| issn | 2187-9745 |
| language | English |
| last_indexed | 2024-04-11T07:12:12Z |
| publishDate | 2022-09-01 |
| publisher | The Japan Society of Mechanical Engineers |
| record_format | Article |
| series | Mechanical Engineering Journal |
| spelling | doaj.art-65a7e5e382584abea3d69256c7f1fd1c2022-12-22T04:38:08ZengThe Japan Society of Mechanical EngineersMechanical Engineering Journal2187-97452022-09-019522-0014022-0014010.1299/mej.22-00140mejLayout optimization of the beam spot locations scanned by electromagnets in particle beam therapyYusuke SAKAMOTO0Takayuki NAGASHIMA1Yuki SATO2Kazuhiro IZUI3Shinji NISHIWAKI4Department of Mechanical Engineering and Science, Kyoto UniversityDepartment of Mechanical Engineering and Science, Kyoto UniversityDepartment of Mechanical Engineering and Science, Kyoto UniversityDepartment of Mechanical Engineering and Science, Kyoto UniversityDepartment of Mechanical Engineering and Science, Kyoto UniversityThis paper presents a layout optimization method of the spot locations of pencil beam scanning for particle beam cancer therapy. With the pencil beam scanning technique, the particle beam is scanned from spot to spot in the tumor by using scanning magnets. To provide clinically ideal dose distributions and less-invasive treatment to the patients, both the spot locations and the number of particles given to each spot should be optimized. However, the spot layout is fixed with a lattice pattern in many prior studies. We propose the optimization method to derive the non-lattice spot layout to realize an acceptable dose distribution with a reduced number of spots. With the proposed method, a large enough number of spots were located densely at the initial state, and then the spots with the smallest contribution were removed one by one through iterations. The number of particles given to each spot was determined by solving a quadratic problem. Furthermore, we also propose the idea to accelerate the optimization process by simultaneously removing multiple spots. The algorithm was confirmed by numerical examples of both two-dimensional and three-dimensional cases. The dose quality with the optimized spot layout was better than that with the conventional lattice spot patterns, with all tested cases. In the optimized spot layout, the spots were located on the closed lines which were concentric to the target contour. We also confirmed the proposed method of multiple-remotion can accelerate the optimization process without violating the dose quality.https://www.jstage.jst.go.jp/article/mej/9/5/9_22-00140/_pdf/-char/enlayout optimizationheuristic approachthree-dimensional locationsscanning magnetparticle beam therapy |
| spellingShingle | Yusuke SAKAMOTO Takayuki NAGASHIMA Yuki SATO Kazuhiro IZUI Shinji NISHIWAKI Layout optimization of the beam spot locations scanned by electromagnets in particle beam therapy Mechanical Engineering Journal layout optimization heuristic approach three-dimensional locations scanning magnet particle beam therapy |
| title | Layout optimization of the beam spot locations scanned by electromagnets in particle beam therapy |
| title_full | Layout optimization of the beam spot locations scanned by electromagnets in particle beam therapy |
| title_fullStr | Layout optimization of the beam spot locations scanned by electromagnets in particle beam therapy |
| title_full_unstemmed | Layout optimization of the beam spot locations scanned by electromagnets in particle beam therapy |
| title_short | Layout optimization of the beam spot locations scanned by electromagnets in particle beam therapy |
| title_sort | layout optimization of the beam spot locations scanned by electromagnets in particle beam therapy |
| topic | layout optimization heuristic approach three-dimensional locations scanning magnet particle beam therapy |
| url | https://www.jstage.jst.go.jp/article/mej/9/5/9_22-00140/_pdf/-char/en |
| work_keys_str_mv | AT yusukesakamoto layoutoptimizationofthebeamspotlocationsscannedbyelectromagnetsinparticlebeamtherapy AT takayukinagashima layoutoptimizationofthebeamspotlocationsscannedbyelectromagnetsinparticlebeamtherapy AT yukisato layoutoptimizationofthebeamspotlocationsscannedbyelectromagnetsinparticlebeamtherapy AT kazuhiroizui layoutoptimizationofthebeamspotlocationsscannedbyelectromagnetsinparticlebeamtherapy AT shinjinishiwaki layoutoptimizationofthebeamspotlocationsscannedbyelectromagnetsinparticlebeamtherapy |