Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer’s disease: In Vitro, In Vivo and In Silico approaches

Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer’s disease: In Vitro, In Vivo and In Silico approaches

The current study aims to quantify HPLC-DAD polyphenolics in the crude extracts of Desmodium elegans, evaluating its cholinesterase inhibitory, antioxidant, molecular docking and protective effects against scopolamine-induced amnesia in mice. A total of 16 compounds were identified which include gal...

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Bibliographic Details
Main Authors:	Mater H. Mahnashi, Muhammad Ashraf, Abdulaziz Hassan Alhasaniah, Hammad Ullah, Alam Zeb, Mehreen Ghufran, Shah Fahad, Muhammad Ayaz, Maria Daglia
Format:	Article
Language:	English
Published:	Elsevier 2023-09-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Desmodium elegans DC. Alzheimer’s disease Oxidative stress Amnesia Polyphenolics Molecular docking
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332223009356

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