Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment
<p>Abstract</p> <p>Background</p> <p>Adherence to anti-osteoporosis treatments is poor, exposing treated women to increased fracture risk. Determinants of poor adherence are poorly understood. The study aims to determine physician- and patient- rated treatment complianc...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-08-01
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| Series: | BMC Women's Health |
| Online Access: | http://www.biomedcentral.com/1472-6874/10/26 |
| _version_ | 1830447842160803840 |
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| author | Huas Dominique Debiais Françoise Blotman Francis Cortet Bernard Mercier Florence Rousseaux Chantal Berger Véronique Gaudin Anne-Françoise Cotté François-Emery |
| author_facet | Huas Dominique Debiais Françoise Blotman Francis Cortet Bernard Mercier Florence Rousseaux Chantal Berger Véronique Gaudin Anne-Françoise Cotté François-Emery |
| author_sort | Huas Dominique |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Adherence to anti-osteoporosis treatments is poor, exposing treated women to increased fracture risk. Determinants of poor adherence are poorly understood. The study aims to determine physician- and patient- rated treatment compliance with osteoporosis treatments and to evaluate factors influencing compliance.</p> <p>Methods</p> <p>This was an observational, cross-sectional pharmacoepidemiological study with a randomly-selected sample of 420 GPs, 154 rheumatologists and 110 gynaecologists practicing in France. Investigators included post-menopausal women with a diagnosis of osteoporosis and a treatment initiated in the previous six months. Investigators completed a questionnaire on clinical features, treatments and medical history, and on patient compliance. Patients completed a questionnaire on sociodemographic features, lifestyle, attitudes and knowledge about osteoporosis, treatment compliance, treatment satisfaction and quality of life. Treatment compliance was evaluated with the Morisky Medication-taking Adherence Scale. Variables collected in the questionnaires were evaluated for association with compliance using multivariate logistic regression analysis.</p> <p>Results</p> <p>785 women were evaluated. Physicians considered 95.4% of the sample to be compliant, but only 65.5% of women considered themselves compliant. The correlation between patient and physician perceptions of compliance was low (κ: 0.11 [95% CI: 0.06 to 0.16]). Patient-rated compliance was highest for monthly bisphosphonates (79.7%) and lowest for hormone substitution therapy (50.0%). Six variables were associated with compliance: treatment administration frequency, perceptions of long-term treatment acceptability, perceptions of health consequences of osteoporosis, perceptions of knowledge about osteoporosis, exercise and mental quality of life.</p> <p>Conclusion</p> <p>Compliance to anti-osteoporosis treatments is poor. Reduction of dosing regimen frequency and patient education may be useful ways of improving compliance.</p> |
| first_indexed | 2024-12-21T07:29:31Z |
| format | Article |
| id | doaj.art-65ab5643e4854e69aed6fe63b061d2b2 |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-12-21T07:29:31Z |
| publishDate | 2010-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-65ab5643e4854e69aed6fe63b061d2b22022-12-21T19:11:36ZengBMCBMC Women's Health1472-68742010-08-011012610.1186/1472-6874-10-26Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatmentHuas DominiqueDebiais FrançoiseBlotman FrancisCortet BernardMercier FlorenceRousseaux ChantalBerger VéroniqueGaudin Anne-FrançoiseCotté François-Emery<p>Abstract</p> <p>Background</p> <p>Adherence to anti-osteoporosis treatments is poor, exposing treated women to increased fracture risk. Determinants of poor adherence are poorly understood. The study aims to determine physician- and patient- rated treatment compliance with osteoporosis treatments and to evaluate factors influencing compliance.</p> <p>Methods</p> <p>This was an observational, cross-sectional pharmacoepidemiological study with a randomly-selected sample of 420 GPs, 154 rheumatologists and 110 gynaecologists practicing in France. Investigators included post-menopausal women with a diagnosis of osteoporosis and a treatment initiated in the previous six months. Investigators completed a questionnaire on clinical features, treatments and medical history, and on patient compliance. Patients completed a questionnaire on sociodemographic features, lifestyle, attitudes and knowledge about osteoporosis, treatment compliance, treatment satisfaction and quality of life. Treatment compliance was evaluated with the Morisky Medication-taking Adherence Scale. Variables collected in the questionnaires were evaluated for association with compliance using multivariate logistic regression analysis.</p> <p>Results</p> <p>785 women were evaluated. Physicians considered 95.4% of the sample to be compliant, but only 65.5% of women considered themselves compliant. The correlation between patient and physician perceptions of compliance was low (κ: 0.11 [95% CI: 0.06 to 0.16]). Patient-rated compliance was highest for monthly bisphosphonates (79.7%) and lowest for hormone substitution therapy (50.0%). Six variables were associated with compliance: treatment administration frequency, perceptions of long-term treatment acceptability, perceptions of health consequences of osteoporosis, perceptions of knowledge about osteoporosis, exercise and mental quality of life.</p> <p>Conclusion</p> <p>Compliance to anti-osteoporosis treatments is poor. Reduction of dosing regimen frequency and patient education may be useful ways of improving compliance.</p>http://www.biomedcentral.com/1472-6874/10/26 |
| spellingShingle | Huas Dominique Debiais Françoise Blotman Francis Cortet Bernard Mercier Florence Rousseaux Chantal Berger Véronique Gaudin Anne-Françoise Cotté François-Emery Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment BMC Women's Health |
| title | Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment |
| title_full | Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment |
| title_fullStr | Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment |
| title_full_unstemmed | Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment |
| title_short | Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment |
| title_sort | compliance and treatment satisfaction of post menopausal women treated for osteoporosis compliance with osteoporosis treatment |
| url | http://www.biomedcentral.com/1472-6874/10/26 |
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