The involvement of NLRP3 inflammasome in CUMS-induced AD-like pathological changes and related cognitive decline in mice

The involvement of NLRP3 inflammasome in CUMS-induced AD-like pathological changes and related cognitive decline in mice

Abstract Background Numerous studies have found that inhibiting the expression of NLRP3 inflammasome can significantly improve depressive-like behaviors in mice, but the research on its effect on cognitive decline in depression and its mechanism is still lacking. This study aimed to elucidate the ro...

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Bibliographic Details
Main Authors: Jia-Mei Li, Ting Hu, Xiao-Na Zhou, Ting Zhang, Jia-Hui Guo, Min-Yuan Wang, Yi-Lin Wu, Wen-Jun Su, Chun-Lei Jiang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Neuroinflammation
Subjects:
NLRP3 inflammasome
Depression
Alzheimer’s disease
Cognitive decline
Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-023-02791-0

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