On Complex Formation between 5-Fluorouracil and β-Cyclodextrin in Solution and in the Solid State: IR Markers and Detection of Short-Lived Complexes by Diffusion NMR

On Complex Formation between 5-Fluorouracil and β-Cyclodextrin in Solution and in the Solid State: IR Markers and Detection of Short-Lived Complexes by Diffusion NMR

In this work, the nuclear magnetic resonance (NMR) and IR spectroscopic markers of the complexation between 5-fluorouracil (5-FU) and β-cyclodextrin (β-CD) in solid state and in aqueous solution are investigated. In the attenuated total reflectance(ATR) spectra of 5-FU/β-CD products obtained by phys...

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Bibliographic Details
Main Authors: Daria L. Melnikova, Zilya F. Badrieva, Mikhail A. Kostin, Corina Maller, Monika Stas, Aneta Buczek, Malgorzata A. Broda, Teobald Kupka, Anne-Marie Kelterer, Peter M. Tolstoy, Vladimir D. Skirda
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
5-FU
β-CD
inclusion complex
IR
NMR
molecular modeling
Online Access:https://www.mdpi.com/1420-3049/25/23/5706

Internet

https://www.mdpi.com/1420-3049/25/23/5706

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