Angiopoietin-like-3 knockout protects against glomerulosclerosis in murine adriamycin-induced nephropathy by attenuating podocyte loss

Angiopoietin-like-3 knockout protects against glomerulosclerosis in murine adriamycin-induced nephropathy by attenuating podocyte loss

Abstract Background Angiopoietin-like-3 (Angptl3) knockout is known for its protective effects on podocyte injury and proteinuria in the early stage of adriamycin (ADR) nephropathy. The current study re-evaluated the renoprotective effect of Angptl3 knockout in chronic ADR nephropathy and attempted...

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Bibliographic Details
Main Authors: Rufeng Dai, Haimei Liu, Xinli Han, Junchao Liu, Yihui Zhai, Jia Rao, Qian Shen, Hong Xu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Nephrology
Subjects:
Angiopoietin-like-3 knockout
Glomerulosclerosis
Podocyte loss
Adriamycin-induced nephropathy
Online Access:http://link.springer.com/article/10.1186/s12882-019-1383-1

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