Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives
Dudley Robinson, Miriam O’Kane, Linda Cardozo Department of Urogynaecology, King’s College Hospital, London, UKCorrespondence: Dudley Robinson, Department of Urogynaecology, King’s College Hospital, Suite 8, Level 3, Golden Jubilee Wing, London, SE5 9RS, UK, Tel +447966485503, Email dudley.robinson@...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-05-01
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| Series: | International Journal of Women's Health |
| Subjects: | |
| Online Access: | https://www.dovepress.com/adherence-to-overactive-bladder-syndrome-treatments-recent-development-peer-reviewed-fulltext-article-IJWH |
| _version_ | 1827942319312076800 |
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| author | Robinson D O'Kane M Cardozo L |
| author_facet | Robinson D O'Kane M Cardozo L |
| author_sort | Robinson D |
| collection | DOAJ |
| description | Dudley Robinson, Miriam O’Kane, Linda Cardozo Department of Urogynaecology, King’s College Hospital, London, UKCorrespondence: Dudley Robinson, Department of Urogynaecology, King’s College Hospital, Suite 8, Level 3, Golden Jubilee Wing, London, SE5 9RS, UK, Tel +447966485503, Email dudley.robinson@nhs.netAbstract: Overactive bladder (OAB) is a common and distressing condition which is known to have a significant effect on Health-Related Quality of Life (HRQoL). Whilst all patients complaining of overactive bladder symptoms will, in theory, initially benefit from conservative measures, many will require pharmacological therapy. Antimuscarinics currently remain the most commonly used drugs to treat OAB although compliance and persistence can be poor due to concerns regarding adverse events and lack of efficacy. This review will explore the common management strategies for OAB with a particular focus on patient adherence to therapy including compliance and persistence. The role of antimuscarinics and the B3-agonist, mirabegron, will be considered along with barriers to their efficacy and adoption. For those patients in whom conservative and pharmacological treatment proves ineffective or is unsuitable, the management of refractory OAB will also be considered. In addition, the role of current and future developments will be examined.Keywords: OAB, adherence, compliance, persistence, antimuscarinics, β3 agonists |
| first_indexed | 2024-03-13T09:56:37Z |
| format | Article |
| id | doaj.art-65ae77a5d46841d9a905a0d5a4230fac |
| institution | Directory Open Access Journal |
| issn | 1179-1411 |
| language | English |
| last_indexed | 2024-03-13T09:56:37Z |
| publishDate | 2023-05-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Women's Health |
| spelling | doaj.art-65ae77a5d46841d9a905a0d5a4230fac2023-05-23T18:52:22ZengDove Medical PressInternational Journal of Women's Health1179-14112023-05-01Volume 1579981183935Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future PerspectivesRobinson DO'Kane MCardozo LDudley Robinson, Miriam O’Kane, Linda Cardozo Department of Urogynaecology, King’s College Hospital, London, UKCorrespondence: Dudley Robinson, Department of Urogynaecology, King’s College Hospital, Suite 8, Level 3, Golden Jubilee Wing, London, SE5 9RS, UK, Tel +447966485503, Email dudley.robinson@nhs.netAbstract: Overactive bladder (OAB) is a common and distressing condition which is known to have a significant effect on Health-Related Quality of Life (HRQoL). Whilst all patients complaining of overactive bladder symptoms will, in theory, initially benefit from conservative measures, many will require pharmacological therapy. Antimuscarinics currently remain the most commonly used drugs to treat OAB although compliance and persistence can be poor due to concerns regarding adverse events and lack of efficacy. This review will explore the common management strategies for OAB with a particular focus on patient adherence to therapy including compliance and persistence. The role of antimuscarinics and the B3-agonist, mirabegron, will be considered along with barriers to their efficacy and adoption. For those patients in whom conservative and pharmacological treatment proves ineffective or is unsuitable, the management of refractory OAB will also be considered. In addition, the role of current and future developments will be examined.Keywords: OAB, adherence, compliance, persistence, antimuscarinics, β3 agonistshttps://www.dovepress.com/adherence-to-overactive-bladder-syndrome-treatments-recent-development-peer-reviewed-fulltext-article-IJWHoabadherencecompliancepersistenceantimuscarinicsbeta 3 agonists |
| spellingShingle | Robinson D O'Kane M Cardozo L Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives International Journal of Women's Health oab adherence compliance persistence antimuscarinics beta 3 agonists |
| title | Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives |
| title_full | Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives |
| title_fullStr | Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives |
| title_full_unstemmed | Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives |
| title_short | Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives |
| title_sort | adherence to overactive bladder syndrome treatments recent developments and future perspectives |
| topic | oab adherence compliance persistence antimuscarinics beta 3 agonists |
| url | https://www.dovepress.com/adherence-to-overactive-bladder-syndrome-treatments-recent-development-peer-reviewed-fulltext-article-IJWH |
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