Anatomical Evaluation of Rat and Mouse Simulators for Laboratory Animal Science Courses

According to the European Directive 63/2010/EU, education and training involving living rats and mice are classified as an animal experiment and demands the implementation of the 3Rs. Therefore, as a method of refinement, rat and mouse simulators were developed to serve as an initial training device...

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Main Authors: Giuliano M. Corte, Melanie Humpenöder, Marcel Pfützner, Roswitha Merle, Mechthild Wiegard, Katharina Hohlbaum, Ken Richardson, Christa Thöne-Reineke, Johanna Plendl
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/11/12/3432
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author Giuliano M. Corte
Melanie Humpenöder
Marcel Pfützner
Roswitha Merle
Mechthild Wiegard
Katharina Hohlbaum
Ken Richardson
Christa Thöne-Reineke
Johanna Plendl
author_facet Giuliano M. Corte
Melanie Humpenöder
Marcel Pfützner
Roswitha Merle
Mechthild Wiegard
Katharina Hohlbaum
Ken Richardson
Christa Thöne-Reineke
Johanna Plendl
author_sort Giuliano M. Corte
collection DOAJ
description According to the European Directive 63/2010/EU, education and training involving living rats and mice are classified as an animal experiment and demands the implementation of the 3Rs. Therefore, as a method of refinement, rat and mouse simulators were developed to serve as an initial training device for various techniques, prior to working on living animals. Nevertheless, little is known about the implementation, anatomical correctness, learning efficiency and practical suitability of these simulators. With this in mind, a collaborative research project called “SimulRATor” was initiated to systematically evaluate the existing rat and mouse simulators in a multi-perspective approach. The objective of the study presented here was to identify the anatomical strengths and weaknesses of the available rat and mouse simulators and to determine anatomical requirements for a new anatomically correct rat simulator, specifically adapted to the needs of Laboratory Animal Science (LAS) training courses. Consequently, experts of Veterinary Anatomy and LAS evaluated the anatomy of all currently available rat and mouse simulators. The evaluation showed that compared to the anatomy of living rats and mice, the tails were perceived as the most anatomically realistic body part, followed by the general exterior and the limbs. The heads were rated as the least favored body part.
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spelling doaj.art-65ba46b6d992479c89370310637c1fa22023-11-23T03:26:52ZengMDPI AGAnimals2076-26152021-12-011112343210.3390/ani11123432Anatomical Evaluation of Rat and Mouse Simulators for Laboratory Animal Science CoursesGiuliano M. Corte0Melanie Humpenöder1Marcel Pfützner2Roswitha Merle3Mechthild Wiegard4Katharina Hohlbaum5Ken Richardson6Christa Thöne-Reineke7Johanna Plendl8Institute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, GermanyInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, GermanyInstitute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, GermanyInstitute for Veterinary Epidemiology and Biostatistics, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, GermanyInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, GermanyInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, GermanyCollege of Veterinary Medicine, School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, AustraliaInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, GermanyInstitute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, GermanyAccording to the European Directive 63/2010/EU, education and training involving living rats and mice are classified as an animal experiment and demands the implementation of the 3Rs. Therefore, as a method of refinement, rat and mouse simulators were developed to serve as an initial training device for various techniques, prior to working on living animals. Nevertheless, little is known about the implementation, anatomical correctness, learning efficiency and practical suitability of these simulators. With this in mind, a collaborative research project called “SimulRATor” was initiated to systematically evaluate the existing rat and mouse simulators in a multi-perspective approach. The objective of the study presented here was to identify the anatomical strengths and weaknesses of the available rat and mouse simulators and to determine anatomical requirements for a new anatomically correct rat simulator, specifically adapted to the needs of Laboratory Animal Science (LAS) training courses. Consequently, experts of Veterinary Anatomy and LAS evaluated the anatomy of all currently available rat and mouse simulators. The evaluation showed that compared to the anatomy of living rats and mice, the tails were perceived as the most anatomically realistic body part, followed by the general exterior and the limbs. The heads were rated as the least favored body part.https://www.mdpi.com/2076-2615/11/12/3432evaluationrefinementeducationanatomymanikinsimulator
spellingShingle Giuliano M. Corte
Melanie Humpenöder
Marcel Pfützner
Roswitha Merle
Mechthild Wiegard
Katharina Hohlbaum
Ken Richardson
Christa Thöne-Reineke
Johanna Plendl
Anatomical Evaluation of Rat and Mouse Simulators for Laboratory Animal Science Courses
Animals
evaluation
refinement
education
anatomy
manikin
simulator
title Anatomical Evaluation of Rat and Mouse Simulators for Laboratory Animal Science Courses
title_full Anatomical Evaluation of Rat and Mouse Simulators for Laboratory Animal Science Courses
title_fullStr Anatomical Evaluation of Rat and Mouse Simulators for Laboratory Animal Science Courses
title_full_unstemmed Anatomical Evaluation of Rat and Mouse Simulators for Laboratory Animal Science Courses
title_short Anatomical Evaluation of Rat and Mouse Simulators for Laboratory Animal Science Courses
title_sort anatomical evaluation of rat and mouse simulators for laboratory animal science courses
topic evaluation
refinement
education
anatomy
manikin
simulator
url https://www.mdpi.com/2076-2615/11/12/3432
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