Series of periodic limb movements in sleep and heart rate variability
Introduction The relationship between a series of periodic limb movements in sleep (PLMS) and heart rate variability (HRV) is not clearly established. HRV reflects changes in heart rate (HR) and autonomic nervous system (ANS) tonus as 2 main components: low-frequency HRV (HRV LF) and high-frequency...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2023-03-01
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| Series: | European Psychiatry |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933823006089/type/journal_article |
| _version_ | 1797617486764441600 |
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| author | M. A. Małkiewicz M. Grzywinska E. Eemil Partinen M. Partinen W. J. Cubala P. J. Winklewski M. Sieminski |
| author_facet | M. A. Małkiewicz M. Grzywinska E. Eemil Partinen M. Partinen W. J. Cubala P. J. Winklewski M. Sieminski |
| author_sort | M. A. Małkiewicz |
| collection | DOAJ |
| description |
Introduction
The relationship between a series of periodic limb movements in sleep (PLMS) and heart rate variability (HRV) is not clearly established. HRV reflects changes in heart rate (HR) and autonomic nervous system (ANS) tonus as 2 main components: low-frequency HRV (HRV LF) and high-frequency HRV (HRV HF). An accumulating body of evidence suggests that a single PLMS alters HRV parameters. However, less is known about the impact of HRV changes when a series of PLMS occurs. Both PLMS and HRV have been reported to show associations with cardiovascular and psychiatric diseases.
Objectives
PLMS have been associated with diverse psychiatric diseases in numerous studies. Longitudinal data demonstrate that patients with PLMS have an increased risk of depression and anxiety, and dementia. It should be noted, however, that it remains unclear how a series of PLMS affects the autonomic nervous system, cardiovascular system, and mental health. Therefore, the aim of this study was to verify the hypothesis that a series of PLMS is connected with a higher range of abnormalities in systolic and diastolic blood pressure (SBP and DBP, respectively), with particular interest in HRV HF and HRV LF scores before the series of PLMS and after the end of the series.
Methods
We undertook a retrospective analysis of polysomnography (PSG) and demographic and medical data of 5 patients with a total number of 1348 PLMS. We analyzed HR, HRV LF, HRV HF, systolic blood pressure (SBP), and diastolic blood pressure (DBP) for 10 heartbeats before the series of PLMS and 10 consecutive heartbeats as beat-to-beat measurements. The stage of sleep and duration of limb movement in each PLMS were also assessed. Statistics analysis was performed using IBM SPSS Statistics (v28.0.0.0). The Kruskal–Wallis test was performed to find statistically significant changes from the baseline.
Results
No statistically significant changes in HR, SBP, or DBP were found in our group. HRV changed after the series of 8 PLMS, with both HRV HF and HRV LF increasing.
Conclusions
Our study presents for the first time the co-activation of both HRV HF and HRV LF, pointing toward the possible autonomic dysregulation in patients with a series of PLMS.
Disclosure of Interest
None Declared |
| first_indexed | 2024-03-11T07:56:46Z |
| format | Article |
| id | doaj.art-65ba5f68ac8c4b4bb04673dd9ecb5ec2 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:56:46Z |
| publishDate | 2023-03-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-65ba5f68ac8c4b4bb04673dd9ecb5ec22023-11-17T05:05:38ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S267S26710.1192/j.eurpsy.2023.608Series of periodic limb movements in sleep and heart rate variabilityM. A. Małkiewicz0M. Grzywinska1E. Eemil Partinen2M. Partinen3W. J. Cubala4P. J. Winklewski5M. Sieminski61Department of Psychiatry 2Applied Cognitive Neuroscience Lab, Department of Human Physiology3Neuroinformatics and Artificial Intelligence Lab, Department of Human Physiology, Medical University of Gdansk, Gdansk, Poland4Department of Neurology, Helsinki University Central Hospital5Department of Neurosciences, Clinicum, University of Helsinki, Helsinki, Finland1Department of Psychiatry2Applied Cognitive Neuroscience Lab, Department of Human Physiology6Department of Emergency Medicine, Medical University of Gdansk, Gdansk, Poland Introduction The relationship between a series of periodic limb movements in sleep (PLMS) and heart rate variability (HRV) is not clearly established. HRV reflects changes in heart rate (HR) and autonomic nervous system (ANS) tonus as 2 main components: low-frequency HRV (HRV LF) and high-frequency HRV (HRV HF). An accumulating body of evidence suggests that a single PLMS alters HRV parameters. However, less is known about the impact of HRV changes when a series of PLMS occurs. Both PLMS and HRV have been reported to show associations with cardiovascular and psychiatric diseases. Objectives PLMS have been associated with diverse psychiatric diseases in numerous studies. Longitudinal data demonstrate that patients with PLMS have an increased risk of depression and anxiety, and dementia. It should be noted, however, that it remains unclear how a series of PLMS affects the autonomic nervous system, cardiovascular system, and mental health. Therefore, the aim of this study was to verify the hypothesis that a series of PLMS is connected with a higher range of abnormalities in systolic and diastolic blood pressure (SBP and DBP, respectively), with particular interest in HRV HF and HRV LF scores before the series of PLMS and after the end of the series. Methods We undertook a retrospective analysis of polysomnography (PSG) and demographic and medical data of 5 patients with a total number of 1348 PLMS. We analyzed HR, HRV LF, HRV HF, systolic blood pressure (SBP), and diastolic blood pressure (DBP) for 10 heartbeats before the series of PLMS and 10 consecutive heartbeats as beat-to-beat measurements. The stage of sleep and duration of limb movement in each PLMS were also assessed. Statistics analysis was performed using IBM SPSS Statistics (v28.0.0.0). The Kruskal–Wallis test was performed to find statistically significant changes from the baseline. Results No statistically significant changes in HR, SBP, or DBP were found in our group. HRV changed after the series of 8 PLMS, with both HRV HF and HRV LF increasing. Conclusions Our study presents for the first time the co-activation of both HRV HF and HRV LF, pointing toward the possible autonomic dysregulation in patients with a series of PLMS. Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823006089/type/journal_article |
| spellingShingle | M. A. Małkiewicz M. Grzywinska E. Eemil Partinen M. Partinen W. J. Cubala P. J. Winklewski M. Sieminski Series of periodic limb movements in sleep and heart rate variability European Psychiatry |
| title | Series of periodic limb movements in sleep and heart rate variability |
| title_full | Series of periodic limb movements in sleep and heart rate variability |
| title_fullStr | Series of periodic limb movements in sleep and heart rate variability |
| title_full_unstemmed | Series of periodic limb movements in sleep and heart rate variability |
| title_short | Series of periodic limb movements in sleep and heart rate variability |
| title_sort | series of periodic limb movements in sleep and heart rate variability |
| url | https://www.cambridge.org/core/product/identifier/S0924933823006089/type/journal_article |
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