Initial experience with a novel method for cognitive transperineal magnetic resonance imaging-targeted prostate biopsy
A cognitive magnetic resonance imaging (MRI)-targeted prostate biopsy conducted by an experienced clinician enhances the detection rate of (high-grade) prostate cancer; however, this method is less successful in the hands of inexperienced surgeons. Therefore, an alternative method of conducting a co...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Asian Journal of Andrology |
| Subjects: | |
| Online Access: | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2020;volume=22;issue=4;spage=432;epage=436;aulast=Wang |
| _version_ | 1818419250128224256 |
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| author | Hai-Feng Wang Rui Chen Bi-Ming He Min Qu Yan Wang Heng-Zhi Lin Qing-Song Yang Xu Gao Ying-Hao Sun |
| author_facet | Hai-Feng Wang Rui Chen Bi-Ming He Min Qu Yan Wang Heng-Zhi Lin Qing-Song Yang Xu Gao Ying-Hao Sun |
| author_sort | Hai-Feng Wang |
| collection | DOAJ |
| description | A cognitive magnetic resonance imaging (MRI)-targeted prostate biopsy conducted by an experienced clinician enhances the detection rate of (high-grade) prostate cancer; however, this method is less successful in the hands of inexperienced surgeons. Therefore, an alternative method of conducting a cognitive MRI-targeted biopsy that can be successfully performed by the inexperienced clinicians should be developed. Ninety-six males suspected of prostate cancer were analyzed using systematic biopsy and cognitive MRI-targeted biopsy based on our novel three-dimensional matrix positioning method. Typically, the core principle of the latter procedure was to put the MRI and ultrasound images into the same virtual coordinate system. Afterward, the targeted biopsy was transformed to target a coordinate for the suspected lesion in the MRI. Subsequently, patients were assessed for the presence/absence of prostate cancer or high-grade prostate cancer. According to our results, the overall detection rate of prostate cancer was 70.8% (68/96), and the detection rate of high-grade prostate cancer was 56.3% (54/96). Specifically, the detection rate of prostate cancer by systematic biopsy was 54.2% (52/96) and that by targeted biopsy was 59.4% (57/96; P = 0.560). Clearly, the combined application of targeted biopsy could remarkably increase the detection rates of prostate cancer (P = 0.025) and high-grade prostate cancer (P = 0.009). Taken together, the findings of this study suggest that the combination of systematic biopsy with our three-dimensional matrix positioning-driven cognitive-targeted biopsy is superior to systematic biopsy in detecting prostate cancer and high-grade prostate cancer. |
| first_indexed | 2024-12-14T12:35:35Z |
| format | Article |
| id | doaj.art-65bd47236f4f4761b160a36f823d9400 |
| institution | Directory Open Access Journal |
| issn | 1008-682X 1745-7262 |
| language | English |
| last_indexed | 2024-12-14T12:35:35Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Andrology |
| spelling | doaj.art-65bd47236f4f4761b160a36f823d94002022-12-21T23:01:02ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622020-01-0122443243610.4103/aja.aja_83_19Initial experience with a novel method for cognitive transperineal magnetic resonance imaging-targeted prostate biopsyHai-Feng WangRui ChenBi-Ming HeMin QuYan WangHeng-Zhi LinQing-Song YangXu GaoYing-Hao SunA cognitive magnetic resonance imaging (MRI)-targeted prostate biopsy conducted by an experienced clinician enhances the detection rate of (high-grade) prostate cancer; however, this method is less successful in the hands of inexperienced surgeons. Therefore, an alternative method of conducting a cognitive MRI-targeted biopsy that can be successfully performed by the inexperienced clinicians should be developed. Ninety-six males suspected of prostate cancer were analyzed using systematic biopsy and cognitive MRI-targeted biopsy based on our novel three-dimensional matrix positioning method. Typically, the core principle of the latter procedure was to put the MRI and ultrasound images into the same virtual coordinate system. Afterward, the targeted biopsy was transformed to target a coordinate for the suspected lesion in the MRI. Subsequently, patients were assessed for the presence/absence of prostate cancer or high-grade prostate cancer. According to our results, the overall detection rate of prostate cancer was 70.8% (68/96), and the detection rate of high-grade prostate cancer was 56.3% (54/96). Specifically, the detection rate of prostate cancer by systematic biopsy was 54.2% (52/96) and that by targeted biopsy was 59.4% (57/96; P = 0.560). Clearly, the combined application of targeted biopsy could remarkably increase the detection rates of prostate cancer (P = 0.025) and high-grade prostate cancer (P = 0.009). Taken together, the findings of this study suggest that the combination of systematic biopsy with our three-dimensional matrix positioning-driven cognitive-targeted biopsy is superior to systematic biopsy in detecting prostate cancer and high-grade prostate cancer.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2020;volume=22;issue=4;spage=432;epage=436;aulast=Wangcognitive fusion; targeted biopsy; three-dimensional |
| spellingShingle | Hai-Feng Wang Rui Chen Bi-Ming He Min Qu Yan Wang Heng-Zhi Lin Qing-Song Yang Xu Gao Ying-Hao Sun Initial experience with a novel method for cognitive transperineal magnetic resonance imaging-targeted prostate biopsy Asian Journal of Andrology cognitive fusion; targeted biopsy; three-dimensional |
| title | Initial experience with a novel method for cognitive transperineal magnetic resonance imaging-targeted prostate biopsy |
| title_full | Initial experience with a novel method for cognitive transperineal magnetic resonance imaging-targeted prostate biopsy |
| title_fullStr | Initial experience with a novel method for cognitive transperineal magnetic resonance imaging-targeted prostate biopsy |
| title_full_unstemmed | Initial experience with a novel method for cognitive transperineal magnetic resonance imaging-targeted prostate biopsy |
| title_short | Initial experience with a novel method for cognitive transperineal magnetic resonance imaging-targeted prostate biopsy |
| title_sort | initial experience with a novel method for cognitive transperineal magnetic resonance imaging targeted prostate biopsy |
| topic | cognitive fusion; targeted biopsy; three-dimensional |
| url | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2020;volume=22;issue=4;spage=432;epage=436;aulast=Wang |
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