A YAP/TAZ–ARHGAP29–RhoA Signaling Axis Regulates Podocyte Protrusions and Integrin Adhesions

A YAP/TAZ–ARHGAP29–RhoA Signaling Axis Regulates Podocyte Protrusions and Integrin Adhesions

Glomerular disease due to podocyte malfunction is a major factor in the pathogenesis of chronic kidney disease. Identification of podocyte-specific signaling pathways is therefore a prerequisite to characterizing relevant disease pathways and developing novel treatment approaches. Here, we employed...

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Bibliographic Details
Main Authors: Manuel Rogg, Jasmin I. Maier, Martin Helmstädter, Alena Sammarco, Felix Kliewe, Oliver Kretz, Lisa Weißer, Clara Van Wymersch, Karla Findeisen, Anna L. Koessinger, Olga Tsoy, Jan Baumbach, Markus Grabbert, Martin Werner, Tobias B. Huber, Nicole Endlich, Oliver Schilling, Christoph Schell
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
podocyte
glomerular kidney disease
EPB41L5
Yurt
YAP/TAZ
ARHGAP29
Online Access:https://www.mdpi.com/2073-4409/12/13/1795

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