Changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospital
Background: Chronic suppurative otitis media (CSOM) is a major health issue in developing countries causing persistant problem and may lead to life-threatening complications. This major health issue and its complications can be best avoided by early and effective treatment based on the knowledge of...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2023-01-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/47136 |
| _version_ | 1797973425202921472 |
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| author | Debarati Bhaumik Ganesh Chandra Gayen Ritam Ray |
| author_facet | Debarati Bhaumik Ganesh Chandra Gayen Ritam Ray |
| author_sort | Debarati Bhaumik |
| collection | DOAJ |
| description | Background: Chronic suppurative otitis media (CSOM) is a major health issue in developing countries causing persistant problem and may lead to life-threatening complications. This major health issue and its complications can be best avoided by early and effective treatment based on the knowledge of causative micro-organisms and their antimicrobial sensitivity which ensures prompt clinical recovery.
Aims and Objectives: The aim is to study the recent microbiological pattern of patients with active CSOM and to determine the in vitro antibiotic sensitivity pattern in order to scientifically guide the patient management rather than trying emperical therapy alone.
Materials and Methods: This prospective study was conducted in Otorhinolaryngology and Microbiology Department of a Burdwan Medical College and Hospital, Burdwan, a tertiary care hospital in Burdwan from January 2019 to December 2020 and 117 clinically diagnosed cases of COM were included in this study after through history taking and meticulous clinical examination. Two Aural swabs were collected from the affected ear by an ENT specialist as outpatient department procedure, under strict aseptic precautions using sterile swabs, after cleaning external auditory canal with a spirit swab. In cases with bilateral disease, ear swabs were taken separately from both the ears. Pus swabs collected were immediately sent to microbiology department for aerobic culture and sensitivity as well as mycological study as per standard procedure.
Results: In the present study, the predominant organism which was isolated from the ear swabs of this region was Pseudomonas aeruginosa, followed by Staphylococcus aureus, Proteus mirabilis, Klebsiella pneumoniae, and Escherichia coli. P. aeruginosa showed maximum susceptibility to Colistin, Aztreonam, Piperacillin, and Tazobactum, Polymixin B in decreasing order and showed moderate sensitivity to Levofloxacin and Ceftazidime. Amikacin is found to be the most effective antibiotic against Proteus and Klebsiella spp. isolated from CSOM patients.
Conclusion: Knowledge of the local microorganism pattern and their antibiotic sensitivity is essential to allow effective and cost saving treatment to patients who will lead to reduction in morbidity and mortality. |
| first_indexed | 2024-04-11T04:02:55Z |
| format | Article |
| id | doaj.art-65be83016faa4cc7943fe5eea2bb2a11 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-04-11T04:02:55Z |
| publishDate | 2023-01-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-65be83016faa4cc7943fe5eea2bb2a112023-01-01T14:56:16ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762023-01-01141124130https://doi.org/10.3126/ajms.v14i1.47136Changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospitalDebarati Bhaumik 0https://orcid.org/0000-0002-1442-0220Ganesh Chandra Gayen 1https://orcid.org/0000-0002-2372-9633Ritam Ray 2https://orcid.org/0000-0003-3919-7587Post Graduate Student, Department of ENT, Burdwan Medical College, Burdwan, West Bengal, India Associate Professor, Department of ENT, Malda Medical College, Malda, West Bengal, India Associate Professor, Department of ENT, Burdwan Medical College, Burdwan, West Bengal, India Background: Chronic suppurative otitis media (CSOM) is a major health issue in developing countries causing persistant problem and may lead to life-threatening complications. This major health issue and its complications can be best avoided by early and effective treatment based on the knowledge of causative micro-organisms and their antimicrobial sensitivity which ensures prompt clinical recovery. Aims and Objectives: The aim is to study the recent microbiological pattern of patients with active CSOM and to determine the in vitro antibiotic sensitivity pattern in order to scientifically guide the patient management rather than trying emperical therapy alone. Materials and Methods: This prospective study was conducted in Otorhinolaryngology and Microbiology Department of a Burdwan Medical College and Hospital, Burdwan, a tertiary care hospital in Burdwan from January 2019 to December 2020 and 117 clinically diagnosed cases of COM were included in this study after through history taking and meticulous clinical examination. Two Aural swabs were collected from the affected ear by an ENT specialist as outpatient department procedure, under strict aseptic precautions using sterile swabs, after cleaning external auditory canal with a spirit swab. In cases with bilateral disease, ear swabs were taken separately from both the ears. Pus swabs collected were immediately sent to microbiology department for aerobic culture and sensitivity as well as mycological study as per standard procedure. Results: In the present study, the predominant organism which was isolated from the ear swabs of this region was Pseudomonas aeruginosa, followed by Staphylococcus aureus, Proteus mirabilis, Klebsiella pneumoniae, and Escherichia coli. P. aeruginosa showed maximum susceptibility to Colistin, Aztreonam, Piperacillin, and Tazobactum, Polymixin B in decreasing order and showed moderate sensitivity to Levofloxacin and Ceftazidime. Amikacin is found to be the most effective antibiotic against Proteus and Klebsiella spp. isolated from CSOM patients. Conclusion: Knowledge of the local microorganism pattern and their antibiotic sensitivity is essential to allow effective and cost saving treatment to patients who will lead to reduction in morbidity and mortality.https://www.nepjol.info/index.php/AJMS/article/view/47136microbiological profile; chronic suppurative otitis media; pus culture and sensitivity |
| spellingShingle | Debarati Bhaumik Ganesh Chandra Gayen Ritam Ray Changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospital Asian Journal of Medical Sciences microbiological profile; chronic suppurative otitis media; pus culture and sensitivity |
| title | Changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospital |
| title_full | Changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospital |
| title_fullStr | Changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospital |
| title_full_unstemmed | Changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospital |
| title_short | Changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospital |
| title_sort | changing trends in microbiological profile in patients with active chronic suppurative otitis media in rural based tertiary care hospital |
| topic | microbiological profile; chronic suppurative otitis media; pus culture and sensitivity |
| url | https://www.nepjol.info/index.php/AJMS/article/view/47136 |
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