Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients
Gestational diabetes mellitus (GDM) is a vital medical complication of pregnancy in which glucose intolerance is first detected or develops during gestation. GDM is associated with adverse maternal and neonatal outcomes, and contemporarily, several clinical trials have tested their incidence in ante...
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Format: | Article |
Language: | English |
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Journal of Ideas in Health
2020-05-01
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Series: | Journal of Ideas in Health |
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Online Access: | https://jidhealth.com/index.php/jidhealth/article/view/47 |
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author | Sumanta Saha |
author_facet | Sumanta Saha |
author_sort | Sumanta Saha |
collection | DOAJ |
description | Gestational diabetes mellitus (GDM) is a vital medical complication of pregnancy in which glucose intolerance is first detected or develops during gestation. GDM is associated with adverse maternal and neonatal outcomes, and contemporarily, several clinical trials have tested their incidence in antenatal vitamin D receiving GDM patients. Considering their clinical significance, these trials' findings pertaining to the above outcomes require cautious interpretation, in terms of the risk of bias due to missingness. Any such bias in randomized controlled trials (RCT) can contaminate the results of a meta-analysis that extracts data from these RCTs. |
first_indexed | 2024-04-10T12:16:45Z |
format | Article |
id | doaj.art-65bf2096ddee4d21b606d6de32deae41 |
institution | Directory Open Access Journal |
issn | 2645-9248 |
language | English |
last_indexed | 2024-04-10T12:16:45Z |
publishDate | 2020-05-01 |
publisher | Journal of Ideas in Health |
record_format | Article |
series | Journal of Ideas in Health |
spelling | doaj.art-65bf2096ddee4d21b606d6de32deae412023-02-15T16:15:41ZengJournal of Ideas in HealthJournal of Ideas in Health2645-92482020-05-0131Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patientsSumanta Saha0National Institute for Research in Tuberculosis, IndiaGestational diabetes mellitus (GDM) is a vital medical complication of pregnancy in which glucose intolerance is first detected or develops during gestation. GDM is associated with adverse maternal and neonatal outcomes, and contemporarily, several clinical trials have tested their incidence in antenatal vitamin D receiving GDM patients. Considering their clinical significance, these trials' findings pertaining to the above outcomes require cautious interpretation, in terms of the risk of bias due to missingness. Any such bias in randomized controlled trials (RCT) can contaminate the results of a meta-analysis that extracts data from these RCTs.https://jidhealth.com/index.php/jidhealth/article/view/47Gestational diabetes mellitus, Vit D, Randomized Controlled Trials (RCT) |
spellingShingle | Sumanta Saha Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients Journal of Ideas in Health Gestational diabetes mellitus, Vit D, Randomized Controlled Trials (RCT) |
title | Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients |
title_full | Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients |
title_fullStr | Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients |
title_full_unstemmed | Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients |
title_short | Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients |
title_sort | impact of missingness on clinical trials on the effectiveness of antenatal vitamin d supplementation in gestational diabetes mellitus patients |
topic | Gestational diabetes mellitus, Vit D, Randomized Controlled Trials (RCT) |
url | https://jidhealth.com/index.php/jidhealth/article/view/47 |
work_keys_str_mv | AT sumantasaha impactofmissingnessonclinicaltrialsontheeffectivenessofantenatalvitamindsupplementationingestationaldiabetesmellituspatients |