Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients

Gestational diabetes mellitus (GDM) is a vital medical complication of pregnancy in which glucose intolerance is first detected or develops during gestation. GDM is associated with adverse maternal and neonatal outcomes, and contemporarily, several clinical trials have tested their incidence in ante...

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Main Author: Sumanta Saha
Format: Article
Language:English
Published: Journal of Ideas in Health 2020-05-01
Series:Journal of Ideas in Health
Subjects:
Online Access:https://jidhealth.com/index.php/jidhealth/article/view/47
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author Sumanta Saha
author_facet Sumanta Saha
author_sort Sumanta Saha
collection DOAJ
description Gestational diabetes mellitus (GDM) is a vital medical complication of pregnancy in which glucose intolerance is first detected or develops during gestation. GDM is associated with adverse maternal and neonatal outcomes, and contemporarily, several clinical trials have tested their incidence in antenatal vitamin D receiving GDM patients. Considering their clinical significance, these trials' findings pertaining to the above outcomes require cautious interpretation, in terms of the risk of bias due to missingness. Any such bias in randomized controlled trials (RCT) can contaminate the results of a meta-analysis that extracts data from these RCTs.
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spelling doaj.art-65bf2096ddee4d21b606d6de32deae412023-02-15T16:15:41ZengJournal of Ideas in HealthJournal of Ideas in Health2645-92482020-05-0131Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patientsSumanta Saha0National Institute for Research in Tuberculosis, IndiaGestational diabetes mellitus (GDM) is a vital medical complication of pregnancy in which glucose intolerance is first detected or develops during gestation. GDM is associated with adverse maternal and neonatal outcomes, and contemporarily, several clinical trials have tested their incidence in antenatal vitamin D receiving GDM patients. Considering their clinical significance, these trials' findings pertaining to the above outcomes require cautious interpretation, in terms of the risk of bias due to missingness. Any such bias in randomized controlled trials (RCT) can contaminate the results of a meta-analysis that extracts data from these RCTs.https://jidhealth.com/index.php/jidhealth/article/view/47Gestational diabetes mellitus, Vit D, Randomized Controlled Trials (RCT)
spellingShingle Sumanta Saha
Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients
Journal of Ideas in Health
Gestational diabetes mellitus, Vit D, Randomized Controlled Trials (RCT)
title Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients
title_full Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients
title_fullStr Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients
title_full_unstemmed Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients
title_short Impact of missingness on clinical trials on the effectiveness of antenatal vitamin D supplementation in gestational diabetes mellitus patients
title_sort impact of missingness on clinical trials on the effectiveness of antenatal vitamin d supplementation in gestational diabetes mellitus patients
topic Gestational diabetes mellitus, Vit D, Randomized Controlled Trials (RCT)
url https://jidhealth.com/index.php/jidhealth/article/view/47
work_keys_str_mv AT sumantasaha impactofmissingnessonclinicaltrialsontheeffectivenessofantenatalvitamindsupplementationingestationaldiabetesmellituspatients