n vitro study of antiamoebic effect of methanol extract of mature seeds of Carica papaya on trophozoites of Entamoeba histolytica

Antiamoebic activity of methanol extract of mature seeds of Carica papaya was tested in vitro on axenic culture of Entamoeba histolytica using metronidazole as a reference amoebicidal agent. The MIC of seed extract was > 62.5 µg/mL as compared to < 0.8 µg/mL for metronidazole. The present stud...

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Main Author: Sujit Kumar Sarker, Nilufar Begum, Dinesh Mondal, Md. Abdullah Siddique, Mohammad A. Rashid
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2010-06-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:http://www.banglajol.info/index.php/BJP/article/view/5003/4182
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author Sujit Kumar Sarker, Nilufar Begum, Dinesh Mondal, Md. Abdullah Siddique, Mohammad A. Rashid
author_facet Sujit Kumar Sarker, Nilufar Begum, Dinesh Mondal, Md. Abdullah Siddique, Mohammad A. Rashid
author_sort Sujit Kumar Sarker, Nilufar Begum, Dinesh Mondal, Md. Abdullah Siddique, Mohammad A. Rashid
collection DOAJ
description Antiamoebic activity of methanol extract of mature seeds of Carica papaya was tested in vitro on axenic culture of Entamoeba histolytica using metronidazole as a reference amoebicidal agent. The MIC of seed extract was > 62.5 µg/mL as compared to < 0.8 µg/mL for metronidazole. The present study suggests that the mature seeds of C. papaya have antiamoebic effect but less pronounced than metronidazole.
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spelling doaj.art-65c164a13cb6434b8967be69586ff8e82022-12-21T18:15:13ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-007X1991-00882010-06-01514547n vitro study of antiamoebic effect of methanol extract of mature seeds of Carica papaya on trophozoites of Entamoeba histolyticaSujit Kumar Sarker, Nilufar Begum, Dinesh Mondal, Md. Abdullah Siddique, Mohammad A. RashidAntiamoebic activity of methanol extract of mature seeds of Carica papaya was tested in vitro on axenic culture of Entamoeba histolytica using metronidazole as a reference amoebicidal agent. The MIC of seed extract was > 62.5 µg/mL as compared to < 0.8 µg/mL for metronidazole. The present study suggests that the mature seeds of C. papaya have antiamoebic effect but less pronounced than metronidazole.http://www.banglajol.info/index.php/BJP/article/view/5003/4182AmoebiasisEntamoeba histolyticaCarica papaya
spellingShingle Sujit Kumar Sarker, Nilufar Begum, Dinesh Mondal, Md. Abdullah Siddique, Mohammad A. Rashid
n vitro study of antiamoebic effect of methanol extract of mature seeds of Carica papaya on trophozoites of Entamoeba histolytica
Bangladesh Journal of Pharmacology
Amoebiasis
Entamoeba histolytica
Carica papaya
title n vitro study of antiamoebic effect of methanol extract of mature seeds of Carica papaya on trophozoites of Entamoeba histolytica
title_full n vitro study of antiamoebic effect of methanol extract of mature seeds of Carica papaya on trophozoites of Entamoeba histolytica
title_fullStr n vitro study of antiamoebic effect of methanol extract of mature seeds of Carica papaya on trophozoites of Entamoeba histolytica
title_full_unstemmed n vitro study of antiamoebic effect of methanol extract of mature seeds of Carica papaya on trophozoites of Entamoeba histolytica
title_short n vitro study of antiamoebic effect of methanol extract of mature seeds of Carica papaya on trophozoites of Entamoeba histolytica
title_sort n vitro study of antiamoebic effect of methanol extract of mature seeds of carica papaya on trophozoites of entamoeba histolytica
topic Amoebiasis
Entamoeba histolytica
Carica papaya
url http://www.banglajol.info/index.php/BJP/article/view/5003/4182
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