Meningioma — defining characteristics of the affected Pakistani population
Objective: To ascertain the age and gender differences, treatment, and management of meningiomas across Pakistan. Methods: Data were collected as part of the PBTES, and patients with a histopathological diagnosis of an intracranial meningioma in 2019 that presented at these centres were included...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association
2022-12-01
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| Series: | Journal of the Pakistan Medical Association |
| Online Access: | https://www.ojs.jpma.org.pk/index.php/public_html/article/view/8674 |
| _version_ | 1797820938378543104 |
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| author | Mashal Murad Shah Muhammad Usman Khalid Mohammad Hamza Bajwa Saqib Kamran Bakhshi Saad bin Anis Naveed Zaman Akhunzada Altaf Ali Laghari Muhammad Faraz Raghib Sameen Siddiqi Syed Ather Enam |
| author_facet | Mashal Murad Shah Muhammad Usman Khalid Mohammad Hamza Bajwa Saqib Kamran Bakhshi Saad bin Anis Naveed Zaman Akhunzada Altaf Ali Laghari Muhammad Faraz Raghib Sameen Siddiqi Syed Ather Enam |
| author_sort | Mashal Murad Shah |
| collection | DOAJ |
| description |
Objective: To ascertain the age and gender differences, treatment, and management of meningiomas across Pakistan.
Methods: Data were collected as part of the PBTES, and patients with a histopathological diagnosis of an intracranial meningioma in 2019 that presented at these centres were included in this cohort study sub-analysis. Thirty-two centres participated in the study. Medical students, residents, and faculty collated data from medical records.
Results: Our data indicate that meningiomas constitute 15.6% of all intracranial tumours in Pakistan and occur more often in females (236, 55%) than in males. The mean age at diagnosis was 43.7 ± 19.9 years. Meningiomas had a slightly higher preponderance in the right hemisphere of the brain at 203 (47.32%) tumours and 267 (62.2%) of the tumours in the frontal and parietal lobes. We found that 174 (61.3%) of all meningiomas diagnosed in Pakistan in 2019 were grade I tumours, which was also the most commonly occurring tumour grade. Adjuvant chemoradiotherapy for meningiomas was rarely observed in Pakistan.
Conclusion: The PBTES reveals a low hospital-based incidence of meningiomas in 2019 when compared to the
incidence in high-income countries but found evidence similar to those of other LMICs. Tumour characteristics, such
as location, grading and surgical procedures, were similar to global literature.
Keywords: Meningioma, Chemoradiotherapy, Brain Neoplasms, Epidemiology, Gender traits.
Continue...
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| first_indexed | 2024-03-13T09:45:31Z |
| format | Article |
| id | doaj.art-65c1d154485a40419177684f64fcc1b9 |
| institution | Directory Open Access Journal |
| issn | 0030-9982 |
| language | English |
| last_indexed | 2024-03-13T09:45:31Z |
| publishDate | 2022-12-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj.art-65c1d154485a40419177684f64fcc1b92023-05-25T04:21:08ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822022-12-01721110.47391/JPMA.11-S4-AKUB08Meningioma — defining characteristics of the affected Pakistani populationMashal Murad Shah0Muhammad Usman Khalid 1Mohammad Hamza Bajwa2Saqib Kamran Bakhshi3Saad bin Anis 4Naveed Zaman Akhunzada 5Altaf Ali Laghari 6Muhammad Faraz Raghib7Sameen Siddiqi 8Syed Ather Enam9The Aga Khan University Hospital, Karachi,PakistanThe Aga Khan University Hospital, Karachi,Pakistan. The Aga Khan University Hospital, Karachi,Pakistan. The Aga Khan University Hospital, Karachi, Pakistan Shaukat Khanum Cancer Memorial Hospital, Lahore. Rehman Medical Institute, Hayatabad, Peshawar,Pakistan Aga Khan University Hospital, Karachi, Pakistan. The Aga Khan University Hospital, Karachi,PakistanThe Aga Khan University Hospital, Karachi,PakistanThe Aga Khan University Hospital, Karachi,Pakistan Objective: To ascertain the age and gender differences, treatment, and management of meningiomas across Pakistan. Methods: Data were collected as part of the PBTES, and patients with a histopathological diagnosis of an intracranial meningioma in 2019 that presented at these centres were included in this cohort study sub-analysis. Thirty-two centres participated in the study. Medical students, residents, and faculty collated data from medical records. Results: Our data indicate that meningiomas constitute 15.6% of all intracranial tumours in Pakistan and occur more often in females (236, 55%) than in males. The mean age at diagnosis was 43.7 ± 19.9 years. Meningiomas had a slightly higher preponderance in the right hemisphere of the brain at 203 (47.32%) tumours and 267 (62.2%) of the tumours in the frontal and parietal lobes. We found that 174 (61.3%) of all meningiomas diagnosed in Pakistan in 2019 were grade I tumours, which was also the most commonly occurring tumour grade. Adjuvant chemoradiotherapy for meningiomas was rarely observed in Pakistan. Conclusion: The PBTES reveals a low hospital-based incidence of meningiomas in 2019 when compared to the incidence in high-income countries but found evidence similar to those of other LMICs. Tumour characteristics, such as location, grading and surgical procedures, were similar to global literature. Keywords: Meningioma, Chemoradiotherapy, Brain Neoplasms, Epidemiology, Gender traits. Continue... https://www.ojs.jpma.org.pk/index.php/public_html/article/view/8674 |
| spellingShingle | Mashal Murad Shah Muhammad Usman Khalid Mohammad Hamza Bajwa Saqib Kamran Bakhshi Saad bin Anis Naveed Zaman Akhunzada Altaf Ali Laghari Muhammad Faraz Raghib Sameen Siddiqi Syed Ather Enam Meningioma — defining characteristics of the affected Pakistani population Journal of the Pakistan Medical Association |
| title | Meningioma — defining characteristics of the affected Pakistani population |
| title_full | Meningioma — defining characteristics of the affected Pakistani population |
| title_fullStr | Meningioma — defining characteristics of the affected Pakistani population |
| title_full_unstemmed | Meningioma — defining characteristics of the affected Pakistani population |
| title_short | Meningioma — defining characteristics of the affected Pakistani population |
| title_sort | meningioma defining characteristics of the affected pakistani population |
| url | https://www.ojs.jpma.org.pk/index.php/public_html/article/view/8674 |
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