Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents

There are conflicting results on the effectiveness of pharmacologic interventions for suicide prevention in adolescence. Here, the authors show, in a retrospective registry study from Sweden during 2016–2020, that regional utilization rates of clozapine, electroconvulsive therapy and lithium in 15–1...

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Main Authors: Adrian E. Desai Boström, Peter Andersson, Mathias Rask-Andersen, Håkan Jarbin, Johan Lundberg, Jussi Jokinen
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36973-4
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author Adrian E. Desai Boström
Peter Andersson
Mathias Rask-Andersen
Håkan Jarbin
Johan Lundberg
Jussi Jokinen
author_facet Adrian E. Desai Boström
Peter Andersson
Mathias Rask-Andersen
Håkan Jarbin
Johan Lundberg
Jussi Jokinen
author_sort Adrian E. Desai Boström
collection DOAJ
description There are conflicting results on the effectiveness of pharmacologic interventions for suicide prevention in adolescence. Here, the authors show, in a retrospective registry study from Sweden during 2016–2020, that regional utilization rates of clozapine, electroconvulsive therapy and lithium in 15–19-year-olds were associated with lower excess suicide death rates in male adolescents
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spelling doaj.art-65c30da805614934b741b0053e64744c2023-03-22T11:44:39ZengNature PortfolioNature Communications2041-17232023-03-011411810.1038/s41467-023-36973-4Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescentsAdrian E. Desai Boström0Peter Andersson1Mathias Rask-Andersen2Håkan Jarbin3Johan Lundberg4Jussi Jokinen5Department of Clinical Sciences/Psychiatry, Umeå UniversityDivision of Psychology, Department of Clinical Neuroscience, Karolinska InstitutetDepartment of Immunology, Genetics and Pathology, Uppsala UniversityDepartment of Clinical Sciences Lund, Section of Child and Adolescent Psychiatry, Lund UniversityStockholm Health Care ServicesDepartment of Clinical Sciences/Psychiatry, Umeå UniversityThere are conflicting results on the effectiveness of pharmacologic interventions for suicide prevention in adolescence. Here, the authors show, in a retrospective registry study from Sweden during 2016–2020, that regional utilization rates of clozapine, electroconvulsive therapy and lithium in 15–19-year-olds were associated with lower excess suicide death rates in male adolescentshttps://doi.org/10.1038/s41467-023-36973-4
spellingShingle Adrian E. Desai Boström
Peter Andersson
Mathias Rask-Andersen
Håkan Jarbin
Johan Lundberg
Jussi Jokinen
Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents
Nature Communications
title Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents
title_full Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents
title_fullStr Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents
title_full_unstemmed Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents
title_short Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents
title_sort regional clozapine ect and lithium usage inversely associated with excess suicide rates in male adolescents
url https://doi.org/10.1038/s41467-023-36973-4
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