Olanzapine decreased osteocyte maturation and Wnt/β-catenin signaling during loading of the alveolar bone in rats

Olanzapine decreased osteocyte maturation and Wnt/β-catenin signaling during loading of the alveolar bone in rats

Several studies indicate the influence of olanzapine on bone metabolism; however, the results are contradictory. We evaluated the effects of olanzapine on the Wnt/β-catenin signaling pathway, physiological alveolar bone turnover, and alveolar bone modeling due to an applied orthodontic force. Adul...

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Bibliographic Details
Main Authors: Saranda Disha-Ibrahimi, Borut Furlani, Gorazd Drevenšek, Samo Hudoklin, Janja Marc, Irena Prodan Žitnik, Jakob Sajovic, Martina Drevenšek
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023-01-01
Series:Biomolecules & Biomedicine
Subjects:
Olanzapine
osteocyte maturation
bone turnover
bone modeling
Wnt/β-catenin signaling pathwa
orthodontic force
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/7523

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