Probiotics, prebiotics, and synbiotics in childhood diarrhea
Abstract Acute diarrhea is the second leading cause of morbidity and mortality attributed to infections in children under five years of age worldwide, with 1.7 million annual estimated cases and more than 500,000 deaths. Although hydroelectrolytic replacement is the gold standard in treating diarrhe...
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Divulgação Científica
2024-04-01
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| Series: | Brazilian Journal of Medical and Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100302&lng=en&tlng=en |
| _version_ | 1797194729364914176 |
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| author | E.M.S. Martins L.C. Nascimento da Silva M.S. Carmo |
| author_facet | E.M.S. Martins L.C. Nascimento da Silva M.S. Carmo |
| author_sort | E.M.S. Martins |
| collection | DOAJ |
| description | Abstract Acute diarrhea is the second leading cause of morbidity and mortality attributed to infections in children under five years of age worldwide, with 1.7 million annual estimated cases and more than 500,000 deaths. Although hydroelectrolytic replacement is the gold standard in treating diarrhea, it does not interfere with the restoration of the intestinal microbiota. Several studies have searched for an adequate alternative in restructuring intestinal homeostasis, finding that treatments based on probiotics, prebiotics, and synbiotics are effective, which made such treatments increasingly present in clinical practice by reducing illness duration with minimal side effects. However, there are still controversies regarding some unwanted reactions in patients. The diversity of strains and the peculiarities of the pathogens that cause diarrhea require further studies to develop effective protocols for prevention and treatment. Here, we provide a descriptive review of childhood diarrhea, emphasizing treatment with probiotics, prebiotics, and synbiotics. |
| first_indexed | 2024-04-24T06:00:54Z |
| format | Article |
| id | doaj.art-65c790a250514a1da5649d502824e865 |
| institution | Directory Open Access Journal |
| issn | 1414-431X |
| language | English |
| last_indexed | 2024-04-24T06:00:54Z |
| publishDate | 2024-04-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-65c790a250514a1da5649d502824e8652024-04-23T07:37:30ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research1414-431X2024-04-015710.1590/1414-431x2024e13205Probiotics, prebiotics, and synbiotics in childhood diarrheaE.M.S. Martinshttps://orcid.org/0000-0003-4014-2735L.C. Nascimento da Silvahttps://orcid.org/0000-0002-4206-0904M.S. Carmohttps://orcid.org/0000-0003-0364-1420Abstract Acute diarrhea is the second leading cause of morbidity and mortality attributed to infections in children under five years of age worldwide, with 1.7 million annual estimated cases and more than 500,000 deaths. Although hydroelectrolytic replacement is the gold standard in treating diarrhea, it does not interfere with the restoration of the intestinal microbiota. Several studies have searched for an adequate alternative in restructuring intestinal homeostasis, finding that treatments based on probiotics, prebiotics, and synbiotics are effective, which made such treatments increasingly present in clinical practice by reducing illness duration with minimal side effects. However, there are still controversies regarding some unwanted reactions in patients. The diversity of strains and the peculiarities of the pathogens that cause diarrhea require further studies to develop effective protocols for prevention and treatment. Here, we provide a descriptive review of childhood diarrhea, emphasizing treatment with probiotics, prebiotics, and synbiotics.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100302&lng=en&tlng=enDiarrheaChildProbioticPrebioticSynbioticsSupplement |
| spellingShingle | E.M.S. Martins L.C. Nascimento da Silva M.S. Carmo Probiotics, prebiotics, and synbiotics in childhood diarrhea Brazilian Journal of Medical and Biological Research Diarrhea Child Probiotic Prebiotic Synbiotics Supplement |
| title | Probiotics, prebiotics, and synbiotics in childhood diarrhea |
| title_full | Probiotics, prebiotics, and synbiotics in childhood diarrhea |
| title_fullStr | Probiotics, prebiotics, and synbiotics in childhood diarrhea |
| title_full_unstemmed | Probiotics, prebiotics, and synbiotics in childhood diarrhea |
| title_short | Probiotics, prebiotics, and synbiotics in childhood diarrhea |
| title_sort | probiotics prebiotics and synbiotics in childhood diarrhea |
| topic | Diarrhea Child Probiotic Prebiotic Synbiotics Supplement |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100302&lng=en&tlng=en |
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