Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis
Abstract Background Ovarian cancer is amongst one of the most commonly occurring cancers affecting women, and the leading cause of gynecologic related cancer death. Its poor prognosis and high mortality rates can be attributed to the absence of specific signs and symptoms until advance stages, which...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | BMC Cancer |
| Online Access: | https://doi.org/10.1186/s12885-023-11041-8 |
| _version_ | 1827922937852723200 |
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| author | Zahra Maleki Mohebat Vali Hossein-Ali Nikbakht Soheil Hassanipour Aida Kouhi Saman Sedighi Roya Farokhi Haleh Ghaem |
| author_facet | Zahra Maleki Mohebat Vali Hossein-Ali Nikbakht Soheil Hassanipour Aida Kouhi Saman Sedighi Roya Farokhi Haleh Ghaem |
| author_sort | Zahra Maleki |
| collection | DOAJ |
| description | Abstract Background Ovarian cancer is amongst one of the most commonly occurring cancers affecting women, and the leading cause of gynecologic related cancer death. Its poor prognosis and high mortality rates can be attributed to the absence of specific signs and symptoms until advance stages, which frequently leads to late diagnosis. Survival rate of patients diagnosed with ovarian cancer can be used in order to better assess current standard of care; the aim of this study is to evaluate the survival rate of ovarian cancer patients in Asia. Methods Systematic review was performed on articles that were published by the end of August 2021 in five international databases, including Medline / PubMed, ProQuest, Scopus, Web of Knowledge, and Google Scholar. The Newcastle-Ottawa quality evaluation form was used for cohort studies to evaluate the quality of the articles. The Cochran-Q and I2 tests were used to calculate the heterogeneity of the studies. The Meta-regression analysis was also done according to when the study was published. Results A total of 667 articles were reviewed, from which 108 were included in this study because they passed the criteria. Based on a randomized model, the survival rates of ovarian cancer after 1, 3 and 5 years were respectively 73.65% (95% CI, 68.66–78.64), 61.31% (95% CI, 55.39–67.23) and 59.60% (95% CI, 56.06–63.13). Additionally, based on meta-regression analysis, there was no relationship between the year of study and survival rate. Conclusions The 1-year survival rate was higher than that of 3- and 5-year for ovarian cancer. This study provides invaluable information that can not only help establish better standard of care for treatment of ovarian cancer, but also assist in development of superior health interventions for prevention and treatment of the disease. |
| first_indexed | 2024-03-13T04:49:28Z |
| format | Article |
| id | doaj.art-65ccc1c55dce4f488825215dd21dc793 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-03-13T04:49:28Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-65ccc1c55dce4f488825215dd21dc7932023-06-18T11:16:44ZengBMCBMC Cancer1471-24072023-06-0123111110.1186/s12885-023-11041-8Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysisZahra Maleki0Mohebat Vali1Hossein-Ali Nikbakht2Soheil Hassanipour3Aida Kouhi4Saman Sedighi5Roya Farokhi6Haleh Ghaem7Student Research Committee, Shiraz University of Medical SciencesStudent Research Committee, Shiraz University of Medical SciencesSocial Determinants of Health Research Center, Health Research Institute, Department of Biostatistics & Epidemiology, School of Public Health, Babol University of Medical SciencesGastrointestinal and Liver Diseases Research Center, Guilan University of Medical SciencesDepartment of Pathology, Keck School of Medicine, University of Southern CaliforniaDepartment of Neurosurgery, Keck school of Medicine, University of Southern CaliforniaDepartment of Health, Health Systems Research, Health Research Institute, Babol University of Medical SciencesNon-Communicable Diseases Research Center, Shiraz University of Medical SciencesAbstract Background Ovarian cancer is amongst one of the most commonly occurring cancers affecting women, and the leading cause of gynecologic related cancer death. Its poor prognosis and high mortality rates can be attributed to the absence of specific signs and symptoms until advance stages, which frequently leads to late diagnosis. Survival rate of patients diagnosed with ovarian cancer can be used in order to better assess current standard of care; the aim of this study is to evaluate the survival rate of ovarian cancer patients in Asia. Methods Systematic review was performed on articles that were published by the end of August 2021 in five international databases, including Medline / PubMed, ProQuest, Scopus, Web of Knowledge, and Google Scholar. The Newcastle-Ottawa quality evaluation form was used for cohort studies to evaluate the quality of the articles. The Cochran-Q and I2 tests were used to calculate the heterogeneity of the studies. The Meta-regression analysis was also done according to when the study was published. Results A total of 667 articles were reviewed, from which 108 were included in this study because they passed the criteria. Based on a randomized model, the survival rates of ovarian cancer after 1, 3 and 5 years were respectively 73.65% (95% CI, 68.66–78.64), 61.31% (95% CI, 55.39–67.23) and 59.60% (95% CI, 56.06–63.13). Additionally, based on meta-regression analysis, there was no relationship between the year of study and survival rate. Conclusions The 1-year survival rate was higher than that of 3- and 5-year for ovarian cancer. This study provides invaluable information that can not only help establish better standard of care for treatment of ovarian cancer, but also assist in development of superior health interventions for prevention and treatment of the disease.https://doi.org/10.1186/s12885-023-11041-8 |
| spellingShingle | Zahra Maleki Mohebat Vali Hossein-Ali Nikbakht Soheil Hassanipour Aida Kouhi Saman Sedighi Roya Farokhi Haleh Ghaem Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis BMC Cancer |
| title | Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis |
| title_full | Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis |
| title_fullStr | Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis |
| title_full_unstemmed | Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis |
| title_short | Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis |
| title_sort | survival rate of ovarian cancer in asian countries a systematic review and meta analysis |
| url | https://doi.org/10.1186/s12885-023-11041-8 |
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