Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical Perspective

In December 2019, a novel coronavirus had emerged in Wuhan city, China that led to an outbreak resulting in a global pandemic, taking thousands of lives. The infectious virus was later classified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Individuals infected by this novel viru...

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Main Authors: Charles Arvind Sethuraman Vairavan, Devarani Rameshnathan, Nagaraja Suryadevara, Gnanendra Shanmugam
Format: Article
Language:English
Published: Journal of Pure and Applied Microbiology 2021-12-01
Series:Journal of Pure and Applied Microbiology
Subjects:
Online Access:https://microbiologyjournal.org/global-pandemic-as-a-result-of-severe-acute-respiratory-syndrome-coronavirus-2-outbreak-a-biomedical-perspective/
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author Charles Arvind Sethuraman Vairavan
Devarani Rameshnathan
Nagaraja Suryadevara
Gnanendra Shanmugam
author_facet Charles Arvind Sethuraman Vairavan
Devarani Rameshnathan
Nagaraja Suryadevara
Gnanendra Shanmugam
author_sort Charles Arvind Sethuraman Vairavan
collection DOAJ
description In December 2019, a novel coronavirus had emerged in Wuhan city, China that led to an outbreak resulting in a global pandemic, taking thousands of lives. The infectious virus was later classified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Individuals infected by this novel virus initially exhibit nonspecific symptoms such as dry cough, fever, dizziness and many more bodily complications. From the “public health emergency of international concern” declaration by the World Health Organisation (WHO), several countries have taken steps in controlling the transmission and many researchers share their knowledge on the SARS-COV-2 characteristics and viral life cycle, that may aid in pharmaceutical and biopharmaceutical companies to develop SARS-CoV-2 vaccine and antiviral drugs that interfere with the viral life cycle. In this literature review the origin, classification, aetiology, life cycle, clinical manifestations, laboratory diagnosis and treatment are all reviewed.
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spelling doaj.art-65cd63059c044b62896f2dd09c3d1b892022-12-21T22:43:22ZengJournal of Pure and Applied MicrobiologyJournal of Pure and Applied Microbiology0973-75102581-690X2021-12-011541759178010.22207/JPAM.15.4.53Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical PerspectiveCharles Arvind Sethuraman Vairavanhttps://orcid.org/0000-0002-4318-3535Devarani Rameshnathanhttps://orcid.org/0000-0002-9648-4999Nagaraja Suryadevarahttps://orcid.org/0000-0002-3553-7567Gnanendra Shanmugamhttps://orcid.org/0000-0001-6617-1804In December 2019, a novel coronavirus had emerged in Wuhan city, China that led to an outbreak resulting in a global pandemic, taking thousands of lives. The infectious virus was later classified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Individuals infected by this novel virus initially exhibit nonspecific symptoms such as dry cough, fever, dizziness and many more bodily complications. From the “public health emergency of international concern” declaration by the World Health Organisation (WHO), several countries have taken steps in controlling the transmission and many researchers share their knowledge on the SARS-COV-2 characteristics and viral life cycle, that may aid in pharmaceutical and biopharmaceutical companies to develop SARS-CoV-2 vaccine and antiviral drugs that interfere with the viral life cycle. In this literature review the origin, classification, aetiology, life cycle, clinical manifestations, laboratory diagnosis and treatment are all reviewed.https://microbiologyjournal.org/global-pandemic-as-a-result-of-severe-acute-respiratory-syndrome-coronavirus-2-outbreak-a-biomedical-perspective/coronavirusescovid-19mutationspike proteinmain protease
spellingShingle Charles Arvind Sethuraman Vairavan
Devarani Rameshnathan
Nagaraja Suryadevara
Gnanendra Shanmugam
Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical Perspective
Journal of Pure and Applied Microbiology
coronaviruses
covid-19
mutation
spike protein
main protease
title Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical Perspective
title_full Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical Perspective
title_fullStr Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical Perspective
title_full_unstemmed Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical Perspective
title_short Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical Perspective
title_sort global pandemic as a result of severe acute respiratory syndrome coronavirus 2 outbreak a biomedical perspective
topic coronaviruses
covid-19
mutation
spike protein
main protease
url https://microbiologyjournal.org/global-pandemic-as-a-result-of-severe-acute-respiratory-syndrome-coronavirus-2-outbreak-a-biomedical-perspective/
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AT devaranirameshnathan globalpandemicasaresultofsevereacuterespiratorysyndromecoronavirus2outbreakabiomedicalperspective
AT nagarajasuryadevara globalpandemicasaresultofsevereacuterespiratorysyndromecoronavirus2outbreakabiomedicalperspective
AT gnanendrashanmugam globalpandemicasaresultofsevereacuterespiratorysyndromecoronavirus2outbreakabiomedicalperspective