Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infection
Neisseria gonorrhoeae is the pathogen of gonorrhea. With the widespread use of antibiotics, drug resistance of Neisseria gonorrhoeae is a growing problem. In recent years, drug-resistant strains to the first-line treatment drugs (such as ceftriaxone sodium) have emerged at home and abroad. The WHO h...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of New Medicine
2022-11-01
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| Series: | Xin yixue |
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| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1669968270581-620322838.pdf |
| _version_ | 1811206301849485312 |
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| author | Zhong Jiaojiao, Su Xiaohong |
| author_facet | Zhong Jiaojiao, Su Xiaohong |
| author_sort | Zhong Jiaojiao, Su Xiaohong |
| collection | DOAJ |
| description | Neisseria gonorrhoeae is the pathogen of gonorrhea. With the widespread use of antibiotics, drug resistance of Neisseria gonorrhoeae is a growing problem. In recent years, drug-resistant strains to the first-line treatment drugs (such as ceftriaxone sodium) have emerged at home and abroad. The WHO has included Neisseria gonorrhoeae as one of the priority pathogens in urgent need of new antibiotics. In recent years, a number of studies have been conducted to evaluate the efficacy of novel antibiotics in the treatment of Neisseria gonorrhoeae, including topoisomerase inhibitors, novel macrolides, pleural polypeptides and small molecule antibacterial drugs, etc. In this article, research progress on the structure, in vitro drug sensitivity, drug resistance mutation, clinical trials and adverse reactions of these drugs was reviewed, aiming to provide references for further research on Neisseria gonorrhoeae and their clinical application. |
| first_indexed | 2024-04-12T03:46:23Z |
| format | Article |
| id | doaj.art-65ce80a0ed284c67b4565a89339f2f2b |
| institution | Directory Open Access Journal |
| issn | 0253-9802 |
| language | zho |
| last_indexed | 2024-04-12T03:46:23Z |
| publishDate | 2022-11-01 |
| publisher | Editorial Office of Journal of New Medicine |
| record_format | Article |
| series | Xin yixue |
| spelling | doaj.art-65ce80a0ed284c67b4565a89339f2f2b2022-12-22T03:49:08ZzhoEditorial Office of Journal of New MedicineXin yixue0253-98022022-11-01531179780110.3969/j.issn.0253-9802.2022.11.002Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infectionZhong Jiaojiao, Su Xiaohong0Institute of Dermatology, Peking Union Medical College, Chinese Academy of Medical Sciences, Nanjing 210042, ChinaNeisseria gonorrhoeae is the pathogen of gonorrhea. With the widespread use of antibiotics, drug resistance of Neisseria gonorrhoeae is a growing problem. In recent years, drug-resistant strains to the first-line treatment drugs (such as ceftriaxone sodium) have emerged at home and abroad. The WHO has included Neisseria gonorrhoeae as one of the priority pathogens in urgent need of new antibiotics. In recent years, a number of studies have been conducted to evaluate the efficacy of novel antibiotics in the treatment of Neisseria gonorrhoeae, including topoisomerase inhibitors, novel macrolides, pleural polypeptides and small molecule antibacterial drugs, etc. In this article, research progress on the structure, in vitro drug sensitivity, drug resistance mutation, clinical trials and adverse reactions of these drugs was reviewed, aiming to provide references for further research on Neisseria gonorrhoeae and their clinical application.https://www.xinyixue.cn/fileup/0253-9802/PDF/1669968270581-620322838.pdf|new antibiotics|neisseria gonorrhoeae|gonorrhea|bacterial drug resistance |
| spellingShingle | Zhong Jiaojiao, Su Xiaohong Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infection Xin yixue |new antibiotics|neisseria gonorrhoeae|gonorrhea|bacterial drug resistance |
| title | Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infection |
| title_full | Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infection |
| title_fullStr | Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infection |
| title_full_unstemmed | Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infection |
| title_short | Research progress on new antibiotics in the treatment of Neisseria gonorrhoeae infection |
| title_sort | research progress on new antibiotics in the treatment of neisseria gonorrhoeae infection |
| topic | |new antibiotics|neisseria gonorrhoeae|gonorrhea|bacterial drug resistance |
| url | https://www.xinyixue.cn/fileup/0253-9802/PDF/1669968270581-620322838.pdf |
| work_keys_str_mv | AT zhongjiaojiaosuxiaohong researchprogressonnewantibioticsinthetreatmentofneisseriagonorrhoeaeinfection |