Prevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, Iraq
<strong>Background:</strong> Diabetic foot ulcers (DFUs) are responsible for days of costly hospitalization and are the major cause of medical lower limb amputations. Determining the appropriate antimicrobial therapy for DFUs is highly dependent on recognizing the microorganisms that cau...
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| Format: | Article |
| Language: | English |
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Baqiyatallah University of Medical Sciences
2020-06-01
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| Series: | Hospital Practices and Research |
| Subjects: | |
| Online Access: | http://www.jhpr.ir/article_110777_74b49a6c11605418a9358055228ffa05.pdf |
| _version_ | 1818503429945819136 |
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| author | Aso Qadir Bakhtiar Mahmoud Taha Mahwi Delman Mohammed Raoof Arif Al-Attar Safeen Othman Mahmood |
| author_facet | Aso Qadir Bakhtiar Mahmoud Taha Mahwi Delman Mohammed Raoof Arif Al-Attar Safeen Othman Mahmood |
| author_sort | Aso Qadir |
| collection | DOAJ |
| description | <strong>Background:</strong> Diabetic foot ulcers (DFUs) are responsible for days of costly hospitalization and are the major cause of medical lower limb amputations. Determining the appropriate antimicrobial therapy for DFUs is highly dependent on recognizing the microorganisms that cause them. Many reports have indicated that there has been a remarkable increase in antibiotic resistance.<br /> <strong>Objectives:</strong> The present study examined various cultures of patients with DFUs to detect the prevalence of microorganisms and their antibiotic sensitivity profiles.<br /> <strong>Methods:</strong> This cross-sectional study was carried out on 92 patients with DFUs admitted to Shar Teaching Hospital and Shahid Hemin Teaching Hospital. Wagner Classification was used to assess the severity and location of the DFUs. Patients were asked questions about their practices of foot care and hygiene, and their answers were recorded. Samples required for testing were taken using sterile swabs.<br /> <strong>Results:</strong> A total of 100 microorganisms were isolated from 92 patients with DFUs, 10 of which were polymicrobial and 2 were culture-negative. There was a highly significant association between the isolated gram-negative microorganisms and higher grades of DFU (P < 0.001). A highly significant association was also observed between bad patient knowledge of hygiene practices and gram-negative microorganisms (P < 0.001). Osteomyelitis was present in 40 (43.4%) patients.<br /> <strong>Conclusion:</strong> Among gram-positive and gram-negative bacteria, Staphylococcus spp. and E. coli were, respectively, the most frequent organisms isolated. The antibiotic imipenem was found to be effective against microorganisms. Tetracycline, erythromycin, and ceftriaxone, however, were highly resistant to antibiotics. To sum up, since different microorganisms are involved and multidrug-resistant strains might emerge, clinicians are recommended to take cultures into account before they initiate empirical therapy. |
| first_indexed | 2024-12-10T21:23:54Z |
| format | Article |
| id | doaj.art-65cfe6174c6d4ee5886594075e53086c |
| institution | Directory Open Access Journal |
| issn | 2476-390X 2476-3918 |
| language | English |
| last_indexed | 2024-12-10T21:23:54Z |
| publishDate | 2020-06-01 |
| publisher | Baqiyatallah University of Medical Sciences |
| record_format | Article |
| series | Hospital Practices and Research |
| spelling | doaj.art-65cfe6174c6d4ee5886594075e53086c2022-12-22T01:33:02ZengBaqiyatallah University of Medical SciencesHospital Practices and Research2476-390X2476-39182020-06-0152566310.34172/hpr.2020.11110777Prevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, IraqAso Qadir0Bakhtiar Mahmoud1Taha Mahwi2Delman Mohammed Raoof Arif Al-Attar3Safeen Othman Mahmood4Ministry of Health, Kurdistan Regional Government, Sulaymaniyah, IraqMinistry of Higher Education and Scientific Research, Training Center of Sulaymaniyah, Sulaymaniyah, IraqCollege of Medicine, University of Sulaymaniyah, Sulaymaniyah, IraqCollege of Medicine, University of Sulaymaniyah, Sulaymaniyah, IraqCollege of Medicine, University of Sulaymaniyah, Sulaymaniyah, Iraq<strong>Background:</strong> Diabetic foot ulcers (DFUs) are responsible for days of costly hospitalization and are the major cause of medical lower limb amputations. Determining the appropriate antimicrobial therapy for DFUs is highly dependent on recognizing the microorganisms that cause them. Many reports have indicated that there has been a remarkable increase in antibiotic resistance.<br /> <strong>Objectives:</strong> The present study examined various cultures of patients with DFUs to detect the prevalence of microorganisms and their antibiotic sensitivity profiles.<br /> <strong>Methods:</strong> This cross-sectional study was carried out on 92 patients with DFUs admitted to Shar Teaching Hospital and Shahid Hemin Teaching Hospital. Wagner Classification was used to assess the severity and location of the DFUs. Patients were asked questions about their practices of foot care and hygiene, and their answers were recorded. Samples required for testing were taken using sterile swabs.<br /> <strong>Results:</strong> A total of 100 microorganisms were isolated from 92 patients with DFUs, 10 of which were polymicrobial and 2 were culture-negative. There was a highly significant association between the isolated gram-negative microorganisms and higher grades of DFU (P < 0.001). A highly significant association was also observed between bad patient knowledge of hygiene practices and gram-negative microorganisms (P < 0.001). Osteomyelitis was present in 40 (43.4%) patients.<br /> <strong>Conclusion:</strong> Among gram-positive and gram-negative bacteria, Staphylococcus spp. and E. coli were, respectively, the most frequent organisms isolated. The antibiotic imipenem was found to be effective against microorganisms. Tetracycline, erythromycin, and ceftriaxone, however, were highly resistant to antibiotics. To sum up, since different microorganisms are involved and multidrug-resistant strains might emerge, clinicians are recommended to take cultures into account before they initiate empirical therapy.http://www.jhpr.ir/article_110777_74b49a6c11605418a9358055228ffa05.pdfdiabetesfoot ulcergram-positive bacteriaantibiotic therapy |
| spellingShingle | Aso Qadir Bakhtiar Mahmoud Taha Mahwi Delman Mohammed Raoof Arif Al-Attar Safeen Othman Mahmood Prevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, Iraq Hospital Practices and Research diabetes foot ulcer gram-positive bacteria antibiotic therapy |
| title | Prevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, Iraq |
| title_full | Prevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, Iraq |
| title_fullStr | Prevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, Iraq |
| title_full_unstemmed | Prevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, Iraq |
| title_short | Prevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, Iraq |
| title_sort | prevalence of microorganisms and antibiotic sensitivity among patients with diabetic foot ulcer in sulaimani city iraq |
| topic | diabetes foot ulcer gram-positive bacteria antibiotic therapy |
| url | http://www.jhpr.ir/article_110777_74b49a6c11605418a9358055228ffa05.pdf |
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