Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma
The capacity of contrast-enhanced ultrasound (CEUS) to detect microvessel perfusion has received much attention in cancer imaging since it can be used to evaluate the enhancement patterns of the lesions during all vascular phases in real time, with higher temporal resolution as compared other imagin...
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MDPI AG
2022-01-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/3/481 |
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| author | Mariella Faccia Matteo Garcovich Maria Elena Ainora Laura Riccardi Maurizio Pompili Antonio Gasbarrini Maria Assunta Zocco |
| author_facet | Mariella Faccia Matteo Garcovich Maria Elena Ainora Laura Riccardi Maurizio Pompili Antonio Gasbarrini Maria Assunta Zocco |
| author_sort | Mariella Faccia |
| collection | DOAJ |
| description | The capacity of contrast-enhanced ultrasound (CEUS) to detect microvessel perfusion has received much attention in cancer imaging since it can be used to evaluate the enhancement patterns of the lesions during all vascular phases in real time, with higher temporal resolution as compared other imaging modalities. A rich body of literature has demonstrated the potential usefulness of CEUS in the assessment of HCC in response to both locoregional and systemic therapies. It is useful to evaluate the efficacy of ablation immediately after treatment to provide guidance for the retreatment of residual unablated tumors. In patients treated with transarterial chemoembolization (TACE), CEUS showed a high degree of concordance with computed tomography and magnetic resonance for the differentiation of responders from non-responders. Dynamic CEUS (D-CEUS) has emerged as a promising tool for the depicting changes in tumor perfusion during anti-angiogenetic treatment that can be associated with tumor response and clinical outcome. This article provides a general review of the current literature regarding the usefulness of CEUS in monitoring HCC response to therapy, highlighting the role of the procedure in different stages of the disease. |
| first_indexed | 2024-03-10T00:09:07Z |
| format | Article |
| id | doaj.art-65d2bb9ed2cc4892a38565bda0727900 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T00:09:07Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-65d2bb9ed2cc4892a38565bda07279002023-11-23T16:03:32ZengMDPI AGCancers2072-66942022-01-0114348110.3390/cancers14030481Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular CarcinomaMariella Faccia0Matteo Garcovich1Maria Elena Ainora2Laura Riccardi3Maurizio Pompili4Antonio Gasbarrini5Maria Assunta Zocco6Department of Internal Medicine, SS Annunziata Hospital Sulmona, 67039 Sulmona, ItalyDepartment of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Rome, 00168 Rome, ItalyDepartment of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Rome, 00168 Rome, ItalyDepartment of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Rome, 00168 Rome, ItalyDepartment of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Rome, 00168 Rome, ItalyDepartment of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Rome, 00168 Rome, ItalyDepartment of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Rome, 00168 Rome, ItalyThe capacity of contrast-enhanced ultrasound (CEUS) to detect microvessel perfusion has received much attention in cancer imaging since it can be used to evaluate the enhancement patterns of the lesions during all vascular phases in real time, with higher temporal resolution as compared other imaging modalities. A rich body of literature has demonstrated the potential usefulness of CEUS in the assessment of HCC in response to both locoregional and systemic therapies. It is useful to evaluate the efficacy of ablation immediately after treatment to provide guidance for the retreatment of residual unablated tumors. In patients treated with transarterial chemoembolization (TACE), CEUS showed a high degree of concordance with computed tomography and magnetic resonance for the differentiation of responders from non-responders. Dynamic CEUS (D-CEUS) has emerged as a promising tool for the depicting changes in tumor perfusion during anti-angiogenetic treatment that can be associated with tumor response and clinical outcome. This article provides a general review of the current literature regarding the usefulness of CEUS in monitoring HCC response to therapy, highlighting the role of the procedure in different stages of the disease.https://www.mdpi.com/2072-6694/14/3/481dynamic contrast-enhanced ultrasoundcontrast-enhanced ultrasoundhepatocellular carcinomatumor response |
| spellingShingle | Mariella Faccia Matteo Garcovich Maria Elena Ainora Laura Riccardi Maurizio Pompili Antonio Gasbarrini Maria Assunta Zocco Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma Cancers dynamic contrast-enhanced ultrasound contrast-enhanced ultrasound hepatocellular carcinoma tumor response |
| title | Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma |
| title_full | Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma |
| title_fullStr | Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma |
| title_full_unstemmed | Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma |
| title_short | Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma |
| title_sort | contrast enhanced ultrasound for monitoring treatment response in different stages of hepatocellular carcinoma |
| topic | dynamic contrast-enhanced ultrasound contrast-enhanced ultrasound hepatocellular carcinoma tumor response |
| url | https://www.mdpi.com/2072-6694/14/3/481 |
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