Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

Abstract Background Two acute respiratory distress syndrome (ARDS) trials showed no benefit for statin therapy, though secondary analyses suggest inflammatory subphenotypes may have a differential response to simvastatin. Statin medications decrease cholesterol levels, and low cholesterol has been a...

Full description

Bibliographic Details
Main Authors: Shaun M. Pienkos, Andrew R. Moore, Jiazhen Guan, Joseph E. Levitt, Michael A. Matthay, Rebecca M. Baron, John Conlon, Daniel F. McAuley, Cecilia M. O’Kane, Angela J. Rogers
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Critical Care
Subjects:
Acute respiratory distress syndrome
Sepsis
Statins
Cholesterol
Critical care
Online Access:https://doi.org/10.1186/s13054-023-04387-9

Internet

https://doi.org/10.1186/s13054-023-04387-9

Similar Items