Effects of α-adrenoceptor antagonists on ABCG2/BCRP-mediated resistance and transport.

Effects of α-adrenoceptor antagonists on ABCG2/BCRP-mediated resistance and transport.

Acquired resistance of cancer cells to various chemotherapeutic agents is known as multidrug resistance, and remains a critical factor in the success of cancer treatment. It is necessary to develop the inhibitors for multidrug resistance. The aim of this study was to examine the effects of eight α-a...

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Bibliographic Details
Main Authors: Kohji Takara, Kazuhiro Yamamoto, Mika Matsubara, Tetsuya Minegaki, Minoru Takahashi, Teruyoshi Yokoyama, Katsuhiko Okumura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3280247?pdf=render

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