Mouse Yolk Sac Hematopoiesis
The yolk sac is the first observed site of hematopoiesis during mouse ontogeny. Primitive erythroid cells are the most well-recognized cell lineages produced from this tissue. In addition to primitive erythroid cells, several types of hematopoietic cells are present, including multipotent hematopoie...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-07-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fcell.2018.00080/full |
| _version_ | 1818388772922851328 |
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| author | Toshiyuki Yamane |
| author_facet | Toshiyuki Yamane |
| author_sort | Toshiyuki Yamane |
| collection | DOAJ |
| description | The yolk sac is the first observed site of hematopoiesis during mouse ontogeny. Primitive erythroid cells are the most well-recognized cell lineages produced from this tissue. In addition to primitive erythroid cells, several types of hematopoietic cells are present, including multipotent hematopoietic progenitors. Yolk sac-derived blood cells constitute a transient wave of embryonic and fetal hematopoiesis. However, recent studies have demonstrated that some macrophage and B cell lineages derived from the early yolk sac may persist to adulthood. This review discusses the cellular basis of mouse yolk sac hematopoiesis and its contributions to embryonic and adult hematopoietic systems. |
| first_indexed | 2024-12-14T04:31:09Z |
| format | Article |
| id | doaj.art-65d788f43b0546b2ab50a3abb8ff6f3c |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-12-14T04:31:09Z |
| publishDate | 2018-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-65d788f43b0546b2ab50a3abb8ff6f3c2022-12-21T23:17:05ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2018-07-01610.3389/fcell.2018.00080392316Mouse Yolk Sac HematopoiesisToshiyuki YamaneThe yolk sac is the first observed site of hematopoiesis during mouse ontogeny. Primitive erythroid cells are the most well-recognized cell lineages produced from this tissue. In addition to primitive erythroid cells, several types of hematopoietic cells are present, including multipotent hematopoietic progenitors. Yolk sac-derived blood cells constitute a transient wave of embryonic and fetal hematopoiesis. However, recent studies have demonstrated that some macrophage and B cell lineages derived from the early yolk sac may persist to adulthood. This review discusses the cellular basis of mouse yolk sac hematopoiesis and its contributions to embryonic and adult hematopoietic systems.https://www.frontiersin.org/article/10.3389/fcell.2018.00080/fullyolk sacblood cell developmentembryonic hematopoiesisfetal hematopoiesisB-1 B cellmacrophage |
| spellingShingle | Toshiyuki Yamane Mouse Yolk Sac Hematopoiesis Frontiers in Cell and Developmental Biology yolk sac blood cell development embryonic hematopoiesis fetal hematopoiesis B-1 B cell macrophage |
| title | Mouse Yolk Sac Hematopoiesis |
| title_full | Mouse Yolk Sac Hematopoiesis |
| title_fullStr | Mouse Yolk Sac Hematopoiesis |
| title_full_unstemmed | Mouse Yolk Sac Hematopoiesis |
| title_short | Mouse Yolk Sac Hematopoiesis |
| title_sort | mouse yolk sac hematopoiesis |
| topic | yolk sac blood cell development embryonic hematopoiesis fetal hematopoiesis B-1 B cell macrophage |
| url | https://www.frontiersin.org/article/10.3389/fcell.2018.00080/full |
| work_keys_str_mv | AT toshiyukiyamane mouseyolksachematopoiesis |